UBE2D3 抗体 (N-Term)
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- 抗原 See all UBE2D3 抗体
- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2D3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against UBE2D3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D3
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 147 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
- 别名
- UBE2D3 (UBE2D3 产品)
- 别名
- E2(17)KB3 antibody, UBC4/5 antibody, UBCH5C antibody, eff antibody, fb36f02 antibody, wu:fb36f02 antibody, zgc:56340 antibody, 1100001F19Rik antibody, 9430029A22Rik antibody, AA414951 antibody, UBE2D3P antibody, Xubc4 antibody, e2(17)kb3 antibody, ubc4/5 antibody, ubch5c antibody, ube2d3.1 antibody, ube2d2 antibody, xubc4 antibody, wu:fj13d01 antibody, zgc:73200 antibody, ubiquitin conjugating enzyme E2 D3 antibody, ubiquitin-conjugating enzyme E2D 3 antibody, ubiquitin conjugating enzyme E2 D3 L homeolog antibody, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like antibody, UBE2D3 antibody, ube2d3 antibody, Ube2d3 antibody, LOC100223566 antibody, ube2d3.L antibody, ube2d2l antibody
- 背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Protein Interaction Partner: NHLRC1, DTX2, TRIM63, RNF146, RNF26, RBX1, UBC, RNF5, RNF2, NEDD4, MID1, STUB1, TRIM39, OTUB1, MDM2, RNF111, TRIM33, PRPF19, RNF115, TRIM58, BTRC, MARCH7, NFKBIA, ARIH1, FBXW11, UBE2D3, PARK2, BRCA1, BARD1, UBE3A, MSL1, UBA1, CBLC, SMURF1, RNF130, UBA6, M
Protein Size: 147 - 分子量
- 17 kDa
- 基因ID
- 7323
- NCBI登录号
- NM_003340, NP_003331
- UniProt
- P61077
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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