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UBE2D1 抗体 (Middle Region)

UBE2D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, Pig, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775671
发货至: 中国
  • 抗原 See all UBE2D1 抗体
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    抗原表位
    • 15
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, Pig, 豚鼠, 兔, 斑马鱼
    宿主
    • 42
    • 3
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 15
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2D1 antibody is un-conjugated
    应用范围
    • 34
    • 17
    • 13
    • 13
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    SQWSPALTVS KVLLSICSLL CDPNPDDPLV PDIAQIYKSD KEKYNRHARE
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against UBE2D1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human UBE2D1
    Top Product
    Discover our top product UBE2D1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 147 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    别名
    UBE2D1 (UBE2D1 产品)
    别名
    E2(17)KB1 antibody, SFT antibody, UBC4/5 antibody, UBCH5 antibody, UBCH5A antibody, ube2d1 antibody, wu:fc16h06 antibody, zgc:73096 antibody, e2(17)kb1 antibody, sft antibody, ubc4/5 antibody, ubch5 antibody, ubch5a antibody, ubiquitin conjugating enzyme E2 D1 antibody, ubiquitin-conjugating enzyme E2D 1 antibody, ubiquitin-conjugating enzyme E2D 1b antibody, ubiquitin conjugating enzyme E2 D1 S homeolog antibody, UBE2D1 antibody, Ube2d1 antibody, ube2d1b antibody, ube2d1.S antibody, ube2d1 antibody
    背景
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
    Alias Symbols: E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
    Protein Interaction Partner: RBX1, STUB1, RNF7, RNF14, MID1, MDM2, EP300, CREBBP, ANAPC11, DTL, RNF115, MKRN2, NEDD4L, FAF2, TRIM32, MID2, RNF111, RNF5, RSP5, GPB1, NHLRC1, RFFL, UHRF2, DTX2, ZNRF1, TRIM63, RNF146, FBXO31, RNF26, TRIM39, RNF126, FBXW7, NEDD4, CUL1, CUL3, MKRN3, UBE3A
    Protein Size: 147
    分子量
    16 kDa
    基因ID
    7321
    NCBI登录号
    NM_001204880, NP_003329
    UniProt
    P51668
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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