AMFR 抗体 (C-Term)
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- 抗原 See all AMFR 抗体
- AMFR (Autocrine Motility Factor Receptor (AMFR))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AMFR antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FGEVEVEPSE VEDFEARGSR FSKSADERQR MLVQRKDELL QQARKRFLNK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against AMFR. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR
- Top Product
- Discover our top product AMFR Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 482 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- AMFR (Autocrine Motility Factor Receptor (AMFR))
- 别名
- AMFR (AMFR 产品)
- 别名
- GP78 antibody, RNF45 antibody, gp78 antibody, wu:fi06e06 antibody, wu:fi37e05 antibody, zgc:63893 antibody, rnf45 antibody, autocrine motility factor receptor antibody, autocrine motility factor receptor L homeolog antibody, autocrine motility factor receptor a antibody, autocrine motility factor receptor, amfr antibody, putative autocrine motility factor receptor, amfr antibody, AMFR antibody, Amfr antibody, amfr.L antibody, amfra antibody, amfr antibody, AaeL_AAEL005881 antibody, CpipJ_CPIJ016043 antibody, Smp_047420 antibody
- 背景
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Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM].
Alias Symbols: GP78, RNF45
Protein Interaction Partner: VCP, UBE2G1, HSPA5, ERLIN2, INSIG1, HMGCR, DHFR, AMFR, UBE2D1, UBC, GPI, TRIM25, DGAT2, UBE2K, Ube2g2, NPLOC4, HERPUD1, BAG6, MAVS, YOD1, ADRA1D, DERL2, ADRB2, FAF2, SEC61B, RPN1, STT3A, STT3B, AUP1, MDC1, SNED1, DDOST, GET4, UBXN4, UBL4A, CD82, SARAF, IT
Protein Size: 643 - 分子量
- 73 kDa
- 基因ID
- 267
- NCBI登录号
- NM_013446
- UniProt
- Q9UKV5
- 途径
- ER-Nucleus Signaling
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