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- 抗原 See all RGS18 抗体
- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RGS18 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- METTLLFFSQ INMCESKEKT FFKLIHGSGK EETSKEAKIR AKEKRNRLSL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RGS18. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RGS18
- Top Product
- Discover our top product RGS18 Primary Antibody
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anti-Regulator of G-Protein Signalling 18 (RGS18) (C-Term) antibody
Verified RGS18 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 28-84) antibodyRGS18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 1-235) antibodyRGS18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 41-90) antibodyRGS18 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (N-Term) antibodyRGS18 适用: 人, 大鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 120-169) antibodyRGS18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 235 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
- 别名
- RGS18 (RGS18 产品)
- 别名
- RGS18 antibody, rgs18 antibody, RGS13 antibody, regulator of G-protein signaling 18 antibody, regulator of G protein signaling 18 antibody, RGS18 antibody, rgs18 antibody, LOC100224724 antibody, Rgs18 antibody
- 背景
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RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Alias Symbols: RP11-142L4.1, RGS13
Protein Interaction Partner: APP, GNAQ, GNAI3, GNAI2, GNAI1,
Protein Size: 235 - 分子量
- 26 kDa
- 基因ID
- 64407
- NCBI登录号
- NM_130782, NP_570138
- UniProt
- Q9NS28
- 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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