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COX IV 抗体 (N-Term)

Name: COX IV 抗体 (N-Term)
SKU: ABIN2775574
Availability: OutOfStock

COX4I1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-COX4I1 Antibody Titration: 1. (COX IV 抗体 (N-Term))

IHC

Lanes: Lane 1: 50ug HeLa lysate Lane 2: 50ug 293T lysate Lane 3: 50ug K562 lysate Lane 4: 50ug MDA-MB-231 lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:1000 Gene Name: COX4I1 Submitted by: David Colecchia, Ph. (COX IV 抗体 (N-Term))

COX4I1 antibody - N-terminal region validated by WB using 1. (COX IV 抗体 (N-Term))

Rabbit Anti-COX4I1 Antibody Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (COX IV 抗体 (N-Term))

IHC

IHC

6 images

(3 references)

产品编号 ABIN2775574

发货至: 中国

Datasheet as PDF

抗原 See all COX IV (COX4I1) 抗体

COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
抗原表位
16

14

12

9

8

8

6

5

3

3

2

1

1

1

1

1

1

1

1

1
N-Term
适用
121

54

45

3

3

3

2

1

1

1
人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠
宿主
87

36

2

2
兔
Compatible Secondaries
克隆类型
86

41
多克隆
标记
63

7

7

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
This COX IV antibody is un-conjugated
应用范围
108

40

37

27

26

23

19

19

14

9

6

3

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

AISTSVCVRA HESVVKSEDF SLPAYMDRRD HPLPEVAHVK HLSASQKALK

预测反应

Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 86%

产品特性

This is a rabbit polyclonal antibody against COX4I1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human COX4I1

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COX4I1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (Center) antibody
COX4I1 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 59-169) antibody
COX4I1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 51-169) antibody
COX4I1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), ICC, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 1-169) antibody
COX4I1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4A10 unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 23-169) antibody
COX4I1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibody
COX4I1 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6B3 unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibody
COX4I1 适用: 人, 大鼠 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal 8D8 unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibody
COX4I1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated

anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibody (HRP)
COX4I1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 169 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).

Geerling, Boon, van der Zon, van den Berg, van den Hoek, Lombès, Princen, Havekes, Rensen, Guigas: "Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice." in: Diabetes, Vol. 63, Issue 3, pp. 880-91, (2014) (PubMed).

Snyder, Wang, Patton, Arosio, Levi, Earley, Allen, Connor: "Mitochondrial ferritin in the substantia nigra in restless legs syndrome." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 11, pp. 1193-9, (2009) (PubMed).
抗原

COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

别名

COX4I1 (COX4I1 产品)

别名

COX4 antibody, COX4-1 antibody, COXIV antibody, mg:bb02d03 antibody, zgc:110058 antibody, GB20012 antibody, AL024441 antibody, Cox4 antibody, Cox4a antibody, cox4 antibody, cox4i1 antibody, coxiv antibody, BcDNA:AT07685 antibody, CG10396 antibody, COX IV antibody, CX41 antibody, CX42 antibody, Dmel\CG10396 antibody, IV antibody, cytochrome c oxidase subunit 4I1 antibody, cytochrome c oxidase subunit IV isoform 1 antibody, cytochrome c oxidase subunit 4 isoform 1, mitochondrial antibody, cytochrome c oxidase polypeptide IV antibody, cytochrome c oxidase subunit IV antibody, cytochrome c oxidase subunit 4i1 antibody, cytochrome c oxidase subunit IV isoform 1 S homeolog antibody, Cytochrome c oxidase subunit 4-like antibody, COX4I1 antibody, cox4i1 antibody, LOC412396 antibody, Cox4I1 antibody, LOC780848 antibody, BMEII0322 antibody, RSal33209_1582 antibody, SJAG_00976 antibody, HMPREF0733_11926 antibody, Cox4i1 antibody, cox4i1.S antibody, COX4L antibody

背景

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
Alias Symbols: COX4, COXIV, MGC72016, COX4-1
Protein Interaction Partner: SDCBP, COX1, env, APP, UBC, ICT1, TMBIM4, NELFCD,
Protein Size: 169

分子量

19 kDa

基因ID

1327

NCBI登录号

NM_001861, NP_001852

UniProt

P13073

途径

Proton Transport