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PPP4R2 抗体 (C-Term)

PPP4R2 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775552
发货至: 中国
  • 抗原 See all PPP4R2 抗体
    PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
    抗原表位
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔
    宿主
    • 28
    克隆类型
    • 28
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP4R2 antibody is un-conjugated
    应用范围
    • 20
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DSRCTRQHCT EEDEEEDEEE EEESFMTSRE MIPERKNQEK ESDDALTVNE
    预测反应
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PPP4R2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human PPP4R2
    Top Product
    Discover our top product PPP4R2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 417 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
    别名
    PPP4R2 (PPP4R2 产品)
    背景
    PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
    Alias Symbols: MGC131930, PP4R2
    Protein Interaction Partner: UBC, PAAF1, SMEK1, SF3A1, CCDC6, VASP, CCT3, PSMA1, INPPL1, AMPD2, LRRC47, DSTN, PLIN3, NUBP2, TPM1, TRA2B, IGBP1, CLNS1A, PPP4C, SRRM2, TIPRL, SMEK2, GEMIN4, DDX20,
    Protein Size: 417
    分子量
    47 kDa
    基因ID
    151987
    NCBI登录号
    NM_174907, NP_777567
    UniProt
    Q9NY27
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