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GNAS 抗体 (N-Term)

Name: GNAS 抗体 (N-Term)
SKU: ABIN2775543
Availability: OutOfStock

GNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-GNAS Antibody Titration: 2. (GNAS 抗体 (N-Term))

Host: Mouse Target Name: GNAS Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml (GNAS 抗体 (N-Term))

Rabbit Anti-GNAS Antibody Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (GNAS 抗体 (N-Term))

IHC

Host: Rabbit Target Name: NOP56 Sample Type: MCF7 Antibody Dilution: 1. (GNAS 抗体 (N-Term))

WB Suggested Anti-GNAS Antibody Titration: 1ug/mL Positive Control: HepG2 lysate There is BioGPS gene expression data showing that GNAS is expressed in HepG2 (GNAS 抗体 (N-Term))

IHC

Host: Rabbit Target Name: GNAS Sample Tissue: Human MCF7 Antibody Dilution: 1. (GNAS 抗体 (N-Term))

IHC

Host: Rabbit Target Name: GNAS Sample Type: Human Fetal Heart Antibody Dilution: 1. (GNAS 抗体 (N-Term))

WB Suggested Anti-GNAS antibody Titration: 1 ug/mL Sample Type: Human Jurkat (GNAS 抗体 (N-Term))

WB Suggested Anti-GNAS antibody Titration: 1 ug/mL Sample Type: Human MCF7 (GNAS 抗体 (N-Term))

11 images

产品编号 ABIN2775543

发货至: 中国

Datasheet as PDF

抗原 See all GNAS 抗体

GNAS (GNAS Complex Locus (GNAS))
抗原表位
10

9

8

8

7

5

5

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
75

28

24

10

7

6

6

5

5

4

4

3

3

1

1

1

1

1

1

1
人, 小鼠, 大鼠, Cow, Pig, 兔
宿主
70

9

1
兔
Compatible Secondaries
克隆类型
72

8
多克隆
标记
48

8

7

5

3

3

1

1

1

1

1

1
This GNAS antibody is un-conjugated
应用范围
62

39

26

16

15

8

8

3

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

SGKSTIVKQM RILHVNGFNG DSEKATKVQD IKNNLKEAIE TIVAAMSNLV

预测反应

Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against GNAS. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human GNAS

Top Product

Discover our top product GNAS Primary Antibody
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated

anti-GNAS Complex Locus (GNAS) (N-Term) antibody
GNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) antibody
KO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated

anti-GNAS Complex Locus (GNAS) (AA 310-404) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (Internal Region) antibody
Verified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 287-315), (C-Term) antibody
GNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated

anti-GNAS Complex Locus (GNAS) (AA 286-315), (C-Term) antibody
GNAS 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-GNAS Complex Locus (GNAS) (AA 1-394) antibody
GNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 380 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

GNAS (GNAS Complex Locus (GNAS))

别名

GNAS (GNAS 产品)

背景

Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.This gene has a highly complex imprinted expression pattern. It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5' exons. Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes. However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual. In addition, one of the alternate 5' exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others. An antisense transcript exists, and may regulate imprinting in this region. Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal dominant inheritance pattern requiring maternal transmission for full penetrance. There are RefSeqs representing four transcript variants of this gene. Other transcript variants including four additional exons have been described, however, their full length sequences have not been determined.
Alias Symbols: RP4-543J19.4, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, MGC33735, PHP1A, PHP1B, POH, dJ309F20.1.1, dJ806M20.3.3, NESP, PHP1C
Protein Interaction Partner: PANX1, AXIN1, UBC, FUS, OPTN, PTGIR, HLA-A, ADRB2, NUCB2, NUCB1, LAMTOR1, SLC25A12, GNAQ, GNA11, UBD, TBXA2R, GNB1, AVPR2, SUMO1, PCK1, Ric8b, GNG2, CALM1, Haus1, Trim69, Cbx1, RIC8A, TTC1, SNX13, ADCY5, CRHR1, PTGDR, TSHR, CAV3, HTR6, RGS2, ADCY6, VIPR1,
Protein Size: 380

分子量

42 kDa

基因ID

2778

NCBI登录号

NM_080426, NP_536351

UniProt

Q5FWY2

途径

Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis