Caldesmon 抗体 (C-Term)
-
- 抗原 See all Caldesmon (CALD1) 抗体
- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠, 斑马鱼, Saccharomyces cerevisiae
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Caldesmon antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- VLEEEEQRRK QEEADRKLRE EEEKRRLKEE IERRRAEAAE KRQKMPEDGL
- 预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 85%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against CALD1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CALD1
- Top Product
- Discover our top product CALD1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 793 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
- 别名
- CALD1 (CALD1 产品)
- 别名
- CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, NAG22 antibody, l-Cad antibody, 4833423D12Rik antibody, AI195384 antibody, AV071549 antibody, AW536160 antibody, C920027I18Rik antibody, CALD1 antibody, Caldesmon antibody, caldesmon 1 antibody, CALD1 antibody, Cald1 antibody
- 背景
-
CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CDM, H-CAD, L-CAD, MGC21352, NAG22, HCAD, LCAD
Protein Interaction Partner: TP53, RPA3, RPA2, RPA1, PHAX, FH, EPB41L2, CSNK2A1, LRCH3, PRKACA, PAN2, UBC, HSP90AA1, CALM1, ACTN1, TINF2, POT1, ISG15, TERF1, ARRB1, Poc1b, Cep76, Sass6, Pafah1b1, TERF2, SHC1, CDK1, CALM3, GRB2,
Protein Size: 793 - 分子量
- 93 kDa
- 基因ID
- 800
- NCBI登录号
- NM_033138, NP_149129
- UniProt
- Q05682
- 途径
- Myometrial Relaxation and Contraction
-