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S1PR5 抗体 (N-Term)

S1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775524
发货至: 中国
  • 抗原 See all S1PR5 抗体
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    抗原表位
    • 15
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    N-Term
    适用
    • 50
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    人, 小鼠, 大鼠, 犬, Pig, Cow
    宿主
    • 81
    • 1
    • 1
    克隆类型
    • 82
    • 1
    多克隆
    标记
    • 26
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    This S1PR5 antibody is un-conjugated
    应用范围
    • 45
    • 35
    • 26
    • 26
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    • 10
    • 6
    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI
    预测反应
    Cow: 80%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against EDG8. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human EDG8
    Top Product
    Discover our top product S1PR5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 147 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bock, Pfalzgraff, Weindl: "Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." in: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).

  • 抗原
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    别名
    EDG8 (S1PR5 产品)
    别名
    EDG8 antibody, Edg-8 antibody, S1P5 antibody, SPPR-1 antibody, SPPR-2 antibody, fd11a07 antibody, wu:fd11a07 antibody, zgc:92296 antibody, edg-8 antibody, edg8 antibody, s1p5 antibody, sppr-1 antibody, sppr-2 antibody, xts1p5 antibody, Edg8 antibody, lpB4 antibody, zgc:158362 antibody, sphingosine-1-phosphate receptor 5 antibody, sphingosine-1-phosphate receptor 5a antibody, sphingosine-1-phosphate receptor 5b antibody, S1PR5 antibody, s1pr5a antibody, s1pr5 antibody, S1pr5 antibody, s1pr5b antibody
    背景
    EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
    Alias Symbols: Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2, EDG8
    Protein Interaction Partner: TP63, GNA12, GNAO1, GNAI1, SGPP1,
    Protein Size: 147
    分子量
    16 kDa
    基因ID
    53637
    NCBI登录号
    NM_003339
    UniProt
    Q9H228
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