S1PR5 抗体 (N-Term)
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- 抗原 See all S1PR5 抗体
- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Pig, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S1PR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI
- 预测反应
- Cow: 80%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against EDG8. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EDG8
- Top Product
- Discover our top product S1PR5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 147 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." in: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).
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Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." in: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).
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- 抗原
- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
- 别名
- EDG8 (S1PR5 产品)
- 别名
- EDG8 antibody, Edg-8 antibody, S1P5 antibody, SPPR-1 antibody, SPPR-2 antibody, fd11a07 antibody, wu:fd11a07 antibody, zgc:92296 antibody, edg-8 antibody, edg8 antibody, s1p5 antibody, sppr-1 antibody, sppr-2 antibody, xts1p5 antibody, Edg8 antibody, lpB4 antibody, zgc:158362 antibody, sphingosine-1-phosphate receptor 5 antibody, sphingosine-1-phosphate receptor 5a antibody, sphingosine-1-phosphate receptor 5b antibody, S1PR5 antibody, s1pr5a antibody, s1pr5 antibody, S1pr5 antibody, s1pr5b antibody
- 背景
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EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Alias Symbols: Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2, EDG8
Protein Interaction Partner: TP63, GNA12, GNAO1, GNAI1, SGPP1,
Protein Size: 147 - 分子量
- 16 kDa
- 基因ID
- 53637
- NCBI登录号
- NM_003339
- UniProt
- Q9H228
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