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PPP2R3B 抗体 (C-Term)

PPP2R3B 适用: 人, 小鼠, 犬, Cow, 大鼠, 斑马鱼, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775379
发货至: 中国
  • 抗原 See all PPP2R3B 抗体
    PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))
    抗原表位
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 犬, Cow, 大鼠, 斑马鱼, 豚鼠, 马, 兔
    宿主
    • 29
    • 6
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP2R3B antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    序列
    TFFNIEKYLD HEQKEQISLL RDGDSGGPEL SDWEKYAAEE YDILVAEETA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 77%, Rat: 82%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against PPP2R3B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human PPP2R3B
    Top Product
    Discover our top product PPP2R3B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 575 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • van Kempen, Redpath, Elchebly, Klein, Papadakis, Wilmott, Scolyer, Edqvist, Pontén, Schadendorf, van Rijk, Michiels, Dumay, Helbling-Leclerc, Dessen, Wouters, Stass, Greenwood, Ghanem, van den Oord et al.: "The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene. ..." in: Science translational medicine, Vol. 8, Issue 369, pp. 369ra177, (2016) (PubMed).

  • 抗原
    PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))
    别名
    PPP2R3B (PPP2R3B 产品)
    别名
    NYREN8 antibody, PPP2R3L antibody, PPP2R3LY antibody, PR48 antibody, im:6895423 antibody, si:ch211-269e2.2 antibody, protein phosphatase 2 regulatory subunit B''beta antibody, serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta antibody, protein phosphatase 2, regulatory subunit B'', beta antibody, protein phosphatase 2 regulatory subunit B', beta L homeolog antibody, PPP2R3B antibody, LOC607103 antibody, ppp2r3b antibody, ppp2r3b.L antibody, Ppp2r3b antibody
    背景
    Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. PPP2R3B belongs to the B'' family. The B'' family has been further divided into subfamilies. PPP2R3B belongs to the beta subfamily of regulatory subunit B''.Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: NY-REN-8, PPP2R3L, PPP2R3LY, PR48, NYREN8
    Protein Interaction Partner: DUSP12, UBC, PPP2R1A, CDC6, PPP2R1B, PPP2CA,
    Protein Size: 575
    分子量
    65 kDa
    基因ID
    28227
    NCBI登录号
    NM_013239, NP_037371
    UniProt
    Q9Y5P8
    途径
    PI3K-Akt Signaling, Mitotic G1-G1/S Phases
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