Cytokeratin 1 抗体 (Middle Region)
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- 抗原 See all Cytokeratin 1 (KRT1) 抗体
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 兔, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cytokeratin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GSYGSGSSSG GYRGGSGGGG GGSSGGRGSG GGSSGGSIGG RGSSSGGVKS
- 预测反应
- Dog: 86%, Human: 100%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against KRT1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KRT1
- Top Product
- Discover our top product KRT1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 644 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
- 别名
- KRT1 (KRT1 产品)
- 别名
- CK1 antibody, EHK antibody, EHK1 antibody, EPPK antibody, K1 antibody, KRT1A antibody, NEPPK antibody, Krt-2.1 antibody, Krt2-1 antibody, Krt86 antibody, KRT1 antibody, Kb1 antibody, KER1 antibody, CK-1 antibody, Keratin-1 antibody, keratin 1 antibody, KRT1 antibody, Krt1 antibody
- 背景
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KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK
Protein Interaction Partner: MDM2, LGR4, EED, ESR1, ADRB2, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, GRDX, VCAM1, UBC, ITGA4, FN1, CDH1, APOA1, ALB, MAGOH, EIF4A3, KRT10, KRT9, KRT2, SLC25A5, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, UBASH3B, NEDD8, CAND1, DCUN1D1, COPS5, CO
Protein Size: 644 - 分子量
- 66 kDa
- 基因ID
- 3848
- NCBI登录号
- NM_006121, NP_006112
- UniProt
- P04264
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