IDH3A 抗体 (N-Term)
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- 抗原 See all IDH3A 抗体
- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IDH3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MKIFDAAKAP IQWEERNVTA IQGPGGKWMI PSEAKESMDK NKMGLKGPLK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against IDH3A. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IDH3A
- Top Product
- Discover our top product IDH3A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 366 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).
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Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).
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- 抗原
- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
- 别名
- IDH3A (IDH3A 产品)
- 别名
- idh3a antibody, MGC76128 antibody, IDH3A antibody, zgc:56380 antibody, zgc:85631 antibody, BG1 antibody, 1110003P10Rik antibody, 1500012E04Rik antibody, AA407078 antibody, AI316514 antibody, isocitrate dehydrogenase 3 (NAD+) alpha antibody, isocitrate dehydrogenase 3 (NAD(+)) alpha antibody, isocitrate dehydrogenase 3 (NAD+) alpha S homeolog antibody, idh3a antibody, IDH3A antibody, idh3a.S antibody, Idh3a antibody
- 背景
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Protein Interaction Partner: HUWE1, SUMO2, STAU1, UBC, MDM2, ADRB2, gag-pol, RAB4A, MBNL1, S100A16, SUCLA2, UQCRFS1P1, SUMO4, EBNA-LP, MYC, TERF2, TERF1, PSMD4, DDA1, DMWD, IDH3B, IDH3G,
Protein Size: 366 - 分子量
- 40 kDa
- 基因ID
- 3419
- NCBI登录号
- NM_005530, NP_005521
- UniProt
- P50213
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