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alpha Actinin 4 抗体 (C-Term)

Name: alpha Actinin 4 抗体 (C-Term)
SKU: ABIN2775289
Availability: OutOfStock

ACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-ACTN4 Antibody Titration: 0. (alpha Actinin 4 抗体 (C-Term))

Lanes: Lane1: 10 ug ACTN1-GFP transfected COS-7 lysate Lane2: 10 ug ACTN2-GFP transfected COS-7 lysate Lane3: 10 ug ACTN3-GFP transfected COS-7 lysate Lane4: 10 ug ACTN4-GFP transfected COS-7 lysate Primary Antibody Dilution: 1: 1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:5000 Gene Name: ACTN4 Submitted by: Johannes W. (alpha Actinin 4 抗体 (C-Term))

3 images

(1 reference)

产品编号 ABIN2775289

发货至: 中国

Datasheet as PDF

抗原 See all alpha Actinin 4 (ACTN4) 抗体

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
抗原表位
10

6

6

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
91

49

45

8

4

4

3

3

2

2

2

2

1

1

1
人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼
宿主
84

7
兔
Compatible Secondaries
克隆类型
72

18
多克隆
标记
55

6

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This alpha Actinin 4 antibody is un-conjugated
应用范围
68

31

26

17

16

15

14

12

8

2

2

1

1

1

1

1

1
Western Blotting (WB)

序列

DVENDRQGEA EFNRIMSLVD PNHSGLVTFQ AFIDFMSRET TDTDTADQVI

预测反应

Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 79%

产品特性

This is a rabbit polyclonal antibody against ACTN4. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human ACTN4

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anti-Actinin, alpha 4 (ACTN4) (AA 1-269) antibody
ACTN4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (C-Term) antibody
ACTN4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) antibody
ACTN4 适用: 人 WB, IP, IF 宿主: 兔 Monoclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 160-440) antibody
ACTN4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody
ACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) antibody
ACTN4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 1-911) antibody
ACTN4 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibody
ACTN4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 785-813), (C-Term) antibody
ACTN4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15705 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 911 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
抗原

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

别名

ACTN4 (ACTN4 产品)

别名

fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody

背景

Alpha actinins belong to the spectrin superfamily which is a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in its gene have been associated with focal and segmental glomerulosclerosis.Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Alias Symbols: DKFZp686K23158, FSGS, FSGS1, ACTININ-4
Protein Interaction Partner: MYOZ2, HUWE1, UBC, BMP7, ACTN3, SUMO2, SUMO3, GNB2, SUMO1, NEDD8, MDM2, HGS, SF3A3, VCP, CDKN2A, ACTN1, PDLIM1, UBD, IGSF8, ICAM1, CD81, SVIL, Fcho2, POT1, VCAM1, TXN, RPS27, MAPK7, KPNA2, ITGA4, FN1, ESR1, CDH1, TRAF3IP1, FMNL1, NOS3, ACTN2, UBASH3B, SHC
Protein Size: 911

分子量

105 kDa

基因ID

81

NCBI登录号

NM_004924, NP_004915

UniProt

O43707

途径

Proton Transport