BAT1 抗体 (C-Term)
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- 抗原 See all BAT1 (DDX39) 抗体
- BAT1 (DDX39) (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39))
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抗原表位
- C-Term
- 适用
- 人, 大鼠, 犬, 小鼠, Cow, 山羊, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YDMPEDSDTY LHRVARAGRF GTKGLAITFV SDENDAKILN DVQDRFEVNI
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against BAT1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human BAT1
- Top Product
- Discover our top product DDX39 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 428 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Proteomic analysis of BRCA1-depleted cell line reveals a putative role for replication protein A2 up-regulation in BRCA1 breast tumor development." in: Proteomics. Clinical applications, Vol. 4, Issue 5, pp. 489-98, (2010) (PubMed).
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Proteomic analysis of BRCA1-depleted cell line reveals a putative role for replication protein A2 up-regulation in BRCA1 breast tumor development." in: Proteomics. Clinical applications, Vol. 4, Issue 5, pp. 489-98, (2010) (PubMed).
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- 抗原
- BAT1 (DDX39) (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39))
- 别名
- BAT1 (DDX39 产品)
- 背景
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BAT1 is a member of the DEAD protein family of ATP-dependent RNA helicases. Members of this family are involved in a number of cellular functions including initiation of translation, RNA splicing, and ribosome assembly. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This protein is a negative regulator of inflammation. It is also thought to be a translation initiation factor. This gene is a strong candidate gene for rheumatoid arthritis. There are multiple alternatively spliced transcript variants known for this gene but only two have been fully described. Both of these variants encode the same isoform. This gene has been found to have multiple polyadenylation sites.
Alias Symbols: BAT1, UAP56, D6S81E
Protein Interaction Partner: THOC3, THOC2, ALYREF, NCBP1, STAU1, SHFM1, UBC, MDM2, WWOX, SUZ12, EED, RNF2, BMI1, RBBP4, C12orf10, NDRG1, HSPD1, GSR, SRPK2, UBD, VCAM1, ITGA4, IL7R, FN1, ATF2, BARD1, WIBG, MAGOHB, WDR74, VPS33B, LSM4, THOC1, RBM8A, DHX38, TXNL1, UBE3A, RPS7, EIF4A2, R
Protein Size: 428 - 分子量
- 47 kDa
- 基因ID
- 7919
- NCBI登录号
- NM_080598, NP_542165
- UniProt
- Q13838
- 途径
- Ribonucleoprotein Complex Subunit Organization
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