DDX5 抗体 (C-Term)
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- 抗原 See all DDX5 抗体
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SFGSNFVSAG IQTSFRTGNP TGTYQNGYDS TQQYGSNVPN MHNGMNQQAY
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against DDX5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DDX5
- Top Product
- Discover our top product DDX5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 614 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).
: "Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 4, pp. M111.015313, (2012) (PubMed).
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The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).
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- 抗原
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
- 别名
- DDX5 (DDX5 产品)
- 别名
- G17P1 antibody, HLR1 antibody, HUMP68 antibody, p68 antibody, 2600009A06Rik antibody, Hlr1 antibody, wu:fa56a07 antibody, wu:fb11e01 antibody, wu:fb16c10 antibody, wu:fb53b05 antibody, ddx5 antibody, DEAD-box helicase 5 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 5 antibody, DEAD-box helicase 5 L homeolog antibody, DDX5 antibody, Ddx5 antibody, ddx5 antibody, ddx5.L antibody
- 背景
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX5 encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. DDX5 consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.
Alias Symbols: p68, HLR1, G17P1, HUMP68
Protein Interaction Partner: FUS, ESR1, DROSHA, MAPKAPK2, UBC, TP53, TUBGCP3, AURKB, SPRTN, AURKA, SUMO2, SUMO3, MDM2, CEP250, STAU1, RPA3, RPA2, RPA1, EED, EZH2, RNF2, SUZ12, rev, DDX17, PABPC4, PRPSAP1, PIN1, LRSAM1, FKBP10, ERO1L, DBNL, WDR4, PARK2, FBXO6, MAPK10, SP1, TARDBP, UBD
Protein Size: 614 - 分子量
- 68 kDa
- 基因ID
- 1655
- NCBI登录号
- NM_004396, NP_004387
- UniProt
- P17844
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
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