RENT1/UPF1 抗体 (Middle Region)
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- 抗原 See all RENT1/UPF1 (UPF1) 抗体
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RENT1/UPF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- RGTPKGKTGR GGRQKNRFGL PGPSQTNLPN SQASQDVASQ PFSQGALTQG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 83%
- 产品特性
- This is a rabbit polyclonal antibody against UPF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UPF1
- Top Product
- Discover our top product UPF1 Primary Antibody
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anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibody
UPF1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibodyUPF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 578-614), (Middle Region) antibodyUPF1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 301-450) antibodyUPF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 583-612) antibodyUPF1 适用: 人 WB 宿主: 兔 Polyclonal RB8354 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 956-1125) antibodyUPF1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1118 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
- 别名
- UPF1 (UPF1 产品)
- 别名
- HUPF1 antibody, NORF1 antibody, RENT1 antibody, pNORF1 antibody, smg-2 antibody, B430202H16Rik antibody, PNORF-1 antibody, Rent1 antibody, Upflp antibody, rent1 antibody, wu:fi40f07 antibody, wu:fj48a01 antibody, zgc:55472 antibody, Tb05.3C6.50 antibody, AO090012000584 antibody, hupf1 antibody, norf1 antibody, pnorf1 antibody, upf1 antibody, UPF1, RNA helicase and ATPase antibody, UPF1 regulator of nonsense transcripts homolog (yeast) antibody, upf1 regulator of nonsense transcripts homolog (yeast) antibody, regulator of nonsense transcripts 1 antibody, Regulator of nonsense transcripts 1 antibody, UPF1 regulator of nonsense transcripts homolog S homeolog antibody, UPF1 antibody, Upf1 antibody, upf1 antibody, Tc00.1047053511317.30 antibody, Tb927.5.2140 antibody, TVAG_453890 antibody, TVAG_237840 antibody, AOR_1_1018194 antibody, HPB8_739 antibody, smg-2 antibody, upf1.S antibody
- 背景
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UPF1 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. UPF1 is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, RENT1, pNORF1, smg-2
Protein Interaction Partner: UBC, SUMO2, STAU1, CDC37, IVNS1ABP, MOV10, DNA2, POP1, LIN28A, UPF3B, STAU2, UPF2, EZH2, BMI1, SUZ12, RNF2, GNPTG, RHOXF2, ACSS2, NADSYN1, PLEKHB2, PLEKHA5, TARDBP, RPRD2, ABHD16A, NDUFB10, DXO, SMG1, RUVBL2, RBM8A, SMG7, EIF4A3, RUVBL1, GSPT2, SMG5, GSPT
Protein Size: 1118 - 分子量
- 123 kDa
- 基因ID
- 5976
- NCBI登录号
- NM_002911, NP_002902
- UniProt
- Q92900
- 途径
- SARS-CoV-2 Protein Interactome
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