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WWP2 抗体 (Middle Region)

WWP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774931
发货至: 中国
  • 抗原 See all WWP2 抗体
    WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
    抗原表位
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 35
    • 11
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马, 绵羊
    宿主
    • 31
    • 4
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 29
    • 2
    • 2
    • 2
    This WWP2 antibody is un-conjugated
    应用范围
    • 27
    • 13
    • 9
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    EMKYTSEGVR YFVDHNTRTT TFKDPRPGFE SGTKQGSPGA YDRSFRWKYH
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 80%
    产品特性
    This is a rabbit polyclonal antibody against WWP2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human WWP2
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 431 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Rougier, van Bemmelen, Bruce, Jespersen, Gavillet, Apothéloz, Cordonier, Staub, Rotin, Abriel: "Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins." in: American journal of physiology. Cell physiology, Vol. 288, Issue 3, pp. C692-701, (2005) (PubMed).

  • 抗原
    WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
    别名
    WWP2 (WWP2 产品)
    别名
    aip2 antibody, wwp2-like antibody, id:ibd1121 antibody, wu:fo87e10 antibody, zgc:154036 antibody, AIP2 antibody, WWp2-like antibody, 1300010O06Rik antibody, AA690238 antibody, AW554328 antibody, WW domain containing E3 ubiquitin protein ligase 2 antibody, WWP2 antibody, wwp2 antibody, Wwp2 antibody
    背景
    WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: AIP2, WWp2-like
    Protein Interaction Partner: LGALS9B, ANKRD44, FBXL18, VPS37C, PABPC1, RUSC1, HNRNPUL1, WWP2, PAIP1, TRAF4, FAM189A2, PDLIM7, EIF3A, WIPF1, UBE2L3, UBC, SNRPC, PTCH1, SMAD6, SMAD3, EZH2, PTEN, UBE2D3, FBXL15, RNF11, ARRDC1, ARRDC4, ARRDC3, VPS11, UBE2G1, UBE2J2, UBE2E3, UBE2E1, UBE2D
    Protein Size: 431
    分子量
    47 kDa
    基因ID
    11060
    NCBI登录号
    NM_199424, NP_955456
    UniProt
    O00308
    途径
    Negative Regulation of Transporter Activity
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