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WWP1 抗体 (N-Term)

WWP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774928
发货至: 中国
  • 抗原 See all WWP1 抗体
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Pig
    宿主
    • 20
    • 5
    克隆类型
    • 21
    • 4
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWP1 antibody is un-conjugated
    应用范围
    • 15
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ATASPRSDTS NNHSGRLQLQ VTVSSAKLKR KKNWFGTAIY TEVVVDGEIT
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against WWP1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human WWP1
    Top Product
    Discover our top product WWP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 922 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    别名
    WWP1 (WWP1 产品)
    别名
    AIP5 antibody, Tiul1 antibody, hSDRP1 antibody, 8030445B08Rik antibody, SDRP1 antibody, WWP1 antibody, aip5 antibody, tiul1 antibody, hsdrp1 antibody, WW domain containing E3 ubiquitin protein ligase 1 antibody, WWP1 antibody, Wwp1 antibody, wwp1 antibody
    背景
    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. WWP1 is a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WWP1 belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants, however, the full length nature of these transcripts has not been defined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AIP5, DKFZp434D2111, Tiul1, hSDRP1
    Protein Interaction Partner: SMAD3, FBXL18, WWP1, TRAF4, FAM189A2, UBE2L3, UBC, PTCH1, SMAD6, NOTCH1, EZH2, YWHAQ, CPSF6, TRAF6, LAPTM5, SMAD5, HSP90AA1, FBXL15, H2AFY2, PHF20L1, RNF11, ASH2L, PRKAA2, ATN1, LNX1, TP63, PTPN14, ERBB4, NFE2, SMAD7, SMAD4, SMAD2, SMAD1, RUNX2, Axin1, ga
    Protein Size: 922
    分子量
    105 kDa
    基因ID
    11059
    NCBI登录号
    NM_007013, NP_008944
    UniProt
    Q9H0M0
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