RUNX2 抗体 (Middle Region)
(1 reference)-
- 抗原 See all RUNX2 抗体
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUNX2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DTATSDFCLW PSTLSKKSQA GASELGPFSD PRQFPSISSL TESRFSNPRM
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RUNX2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RUNX2
- Top Product
- Discover our top product RUNX2 Primary Antibody
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anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibodyRUNX2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (Internal Region) antibodyRUNX2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 1D2 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 521 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification." in: Kidney international, Vol. 81, Issue 3, pp. 256-65, (2012) (PubMed).
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: "Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification." in: Kidney international, Vol. 81, Issue 3, pp. 256-65, (2012) (PubMed).
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- 抗原
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- 别名
- RUNX2 (RUNX2 产品)
- 别名
- AML3 antibody, CBF-alpha-1 antibody, CBFA1 antibody, CCD antibody, CCD1 antibody, CLCD antibody, OSF-2 antibody, OSF2 antibody, PEA2aA antibody, PEBP2aA antibody, Cbf antibody, Cbfa-1 antibody, Cbfa1 antibody, LS3 antibody, Osf2 antibody, Pebp2a1 antibody, Pebpa2a antibody, runx2 antibody, RUNX2 antibody, ccd antibody, aml3 antibody, ccd1 antibody, osf2 antibody, cbfa1 antibody, pea2aa antibody, pebp2a1 antibody, pebp2a2 antibody, pebp2aa antibody, pebp2aa1 antibody, runt related transcription factor 2 antibody, runt-related transcription factor 2a antibody, runt-related transcription factor 2 antibody, runt related transcription factor 2 L homeolog antibody, RUNX2 antibody, runx2a antibody, Runx2 antibody, runx2 antibody, LOC703331 antibody, LOC100549663 antibody, runx2.L antibody
- 背景
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RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
Alias Symbols: CCD, AML3, CCD1, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1
Protein Interaction Partner: HDAC7, HDAC6, TP53, UBC, RB1, PML, HIF1A, SMURF1, SMAD1, SMURF2, HIVEP3, WWP1, FHL2, UBTF, SUV39H1, HDAC1, STAT3, SMAD3, RBM14, SOX9, NR0B2, EP300, HDAC5, HDAC4, HDAC3, CREBBP, XRCC5, HES1, XRCC6, BMPR1A, KAT2B, TLE1, YAP1, KAT6B, TAF1A, AXIN1, SMAD6, MAP
Protein Size: 521 - 分子量
- 57 kDa
- 基因ID
- 860
- NCBI登录号
- NM_001024630, NP_001019801
- UniProt
- Q13950
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