MCM6 抗体 (C-Term)
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- 抗原 See all MCM6 抗体
- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCM6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- RIIEKVIHRL THYDHVLIEL TQAGLKGSTE GSESYEEDPY LVVNPNYLLE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against MCM6. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MCM6
- Top Product
- Discover our top product MCM6 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 821 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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- 抗原
- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
- 别名
- MCM6 (MCM6 产品)
- 别名
- CG4039 antibody, DmMCM6 antibody, DmeMCM6 antibody, Dmel\\CG4039 antibody, MCM6 antibody, McM6 antibody, fs(1)K1214 antibody, mcm6 antibody, MCG40308 antibody, Mis5 antibody, P105MCM antibody, Mcmd6 antibody, mis5 antibody, mmcm6 antibody, ASP-l1 antibody, D1Wsu22e antibody, Minichromosome maintenance 6 antibody, DNA replication licensing factor MCM6 antibody, minichromosome maintenance complex component 6 antibody, minichromosome maintenance complex component 6 L homeolog antibody, DNA replication licensing factor mcm-6 antibody, Mcm6 antibody, TP02_0113 antibody, PVX_114735 antibody, CMU_027970 antibody, MCM6 antibody, mcm6.L antibody, mcm-6 antibody
- 背景
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The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Alias Symbols: MCG40308, Mis5, P105MCM
Protein Interaction Partner: MCM10, HUWE1, SNRPB2, MCM2, NUDT2, ZBTB9, FAM161A, UBC, SUMO2, SUMO3, MCMBP, POLK, MCM4, MCM3, KPNA3, HSP90AB1, CDKN2A, ACLY, CAP1, ING5, MCM6, BAG3, TONSL, MMS22L, ASF1B, SMC1A, MCM7, CCNA1, VCAM1, ITGA4, FN1, gag-pol, GMNN, ORC6, DBF4, CDC7, PAXIP1, TP5
Protein Size: 821 - 分子量
- 90 kDa
- 基因ID
- 4175
- NCBI登录号
- NM_005915, NP_005906
- UniProt
- Q14566
- 途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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