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Connexin 43/GJA1 抗体 (N-Term)

GJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 斑马鱼, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774853
发货至: 中国
  • 抗原 See all Connexin 43/GJA1 (GJA1) 抗体
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    抗原表位
    • 20
    • 16
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 124
    • 87
    • 82
    • 30
    • 11
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 斑马鱼, 马, 绵羊
    宿主
    • 123
    • 6
    • 3
    • 1
    克隆类型
    • 126
    • 6
    多克隆
    标记
    • 77
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Connexin 43/GJA1 antibody is un-conjugated
    应用范围
    • 91
    • 52
    • 46
    • 22
    • 20
    • 16
    • 13
    • 13
    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    LYLAHVFYVM RKEEKLNKKE EELKVAQTDG VNVDMHLKQI EIKKFKYGIE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against GJA1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human GJA1
    Top Product
    Discover our top product GJA1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 382 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    别名
    GJA1 (GJA1 产品)
    背景
    Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
    Alias Symbols: HSS, CX43, GJAL, ODDD, AVSD3, HLHS1, DFNB38
    Protein Interaction Partner: UBC, STAMBP, EPS15, UBQLN4, PSMD4, PSMD2, S100A1, GJA1, CNST, NEDD4, TJP1, HGS, TSG101, SGSM3, GJA5, MAPK7, MAPK3, CAV1, CSNK1D, SRC, PRKCG, PRKCE, PRKCB, PRKCA, MAPK1, NOV, CSK, GJA3,
    Protein Size: 382
    分子量
    42 kDa
    基因ID
    2697
    NCBI登录号
    NM_000165, NP_000156
    UniProt
    Q53FJ6
    途径
    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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