Annexin VII 抗体 (N-Term)
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- 抗原 See all Annexin VII (ANXA7) 抗体
- Annexin VII (ANXA7) (Annexin A7 (ANXA7))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Annexin VII antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MSYPGYPPTG YPPFPGYPPA GQESSFPPSG QYPYPSGFPP MGGGAYPQVP
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ANXA7. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA7
- Top Product
- Discover our top product ANXA7 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 466 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner." in: Biochimica et biophysica acta, Vol. 1600, Issue 1-2, pp. 61-7, (2002) (PubMed).
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The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner." in: Biochimica et biophysica acta, Vol. 1600, Issue 1-2, pp. 61-7, (2002) (PubMed).
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- 抗原
- Annexin VII (ANXA7) (Annexin A7 (ANXA7))
- 别名
- ANXA7 (ANXA7 产品)
- 别名
- ANX7 antibody, SNX antibody, SYNEXIN antibody, AI265384 antibody, AI316497 antibody, Anx7 antibody, synexin antibody, anxa7 antibody, MGC76267 antibody, MGC82023 antibody, ANXA7 antibody, MGC83033 antibody, annexin A7 antibody, annexin VII antibody, annexin A7 S homeolog antibody, ANXA7 antibody, Anxa7 antibody, anxa7 antibody, anxa7.S antibody, PTRG_02166 antibody, BRAFLDRAFT_231082 antibody, PAAG_00136 antibody, MCYG_04180 antibody, VDBG_06328 antibody, MGYG_02426 antibody
- 背景
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ANXA7 is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. The selection of poly(A) signals is independent of the mRNA splicing pattern. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
Alias Symbols: SNX, ANX7, SYNEXIN
Protein Interaction Partner: UBC, PAX8, ATP4A, SRC, Prkcb, Prkcg, Prkca, PRKG1, PRKACA, VCP, ANXA4, CUL4B, CUL5, ALG2, ELAVL1, CCDC90B, WDR18, LRIF1, OTUB1, CPSF3L, SEMA5B, INPP5K, ACTL6B, CSAD, SDF4, MED31, TAF5L, TRMT2A, TUBB2B, CPNE2, ZNF431, KLHL23, DOCK7, WDR73, FBN3, RBM48, ADA
Protein Size: 466 - 分子量
- 51 kDa
- 基因ID
- 310
- NCBI登录号
- NM_001156, NP_001147
- UniProt
- Q5T0M6
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