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ADRB1 抗体 (Middle Region)

Name: ADRB1 抗体 (Middle Region)
SKU: ABIN2774823
Availability: OutOfStock

ADRB1 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

Host: Rabbit Target Name: ADRB1 Sample Type: Human Adult Placenta Antibody Dilution: 1. (ADRB1 抗体 (Middle Region))

Host: Rabbit Target Name: ADRB1 Sample Type: Human Fetal Heart Antibody Dilution: 1. (ADRB1 抗体 (Middle Region))

Host: Rabbit Target Name: ADRB1 Sample Type: Human Fetal Lung Antibody Dilution: 1. (ADRB1 抗体 (Middle Region))

Host: Rabbit Target Name: ADRB1 Sample Type: Human Fetal Muscle Antibody Dilution: 1. (ADRB1 抗体 (Middle Region))

WB Suggested Anti-ADRB1 Antibody Positive Control: Lane 1: 20ug Wild type mouse, left ventricle Lane 2: 20ug Transgenic mouse, treated with experimental drug, left ventricle Lane 3: 20ug HepG2 lysate Primary Antibody Dilution : 1:1000 Secondary Antibody : Goat anti rabbit-HRP Secondry Antibody Dilution : 1:5,000 Submitted by: Kathleen Gabrielson (ADRB1 抗体 (Middle Region))

WB Suggested Anti-ADRB1 Antibody Titration: 0. (ADRB1 抗体 (Middle Region))

6 images

(2 references)

产品编号 ABIN2774823

发货至: 中国

Datasheet as PDF

抗原 See all ADRB1 抗体

ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
抗原表位
16

6

4

3

2

2

1

1

1

1

1
Middle Region

适用

人, 小鼠, 大鼠, 犬, Pig, 兔, 豚鼠
宿主
44

1
兔
Compatible Secondaries
克隆类型
45
多克隆
标记
15

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ADRB1 antibody is un-conjugated
应用范围
32

20

13

13

13

7

6

5

3

2

1

1

1
Western Blotting (WB)

序列

CTVWAISALV SFLPILMHWW RAESDEARRC YNDPKCCDFV TNRAYAIASS

预测反应

Dog: 87%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against ADRB1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human ADRB1

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anti-Adrenergic, beta-1-, Receptor (ADRB1) (Internal Region) antibody
Verified ADRB1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody
ADRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 401-477) antibody
ADRB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 150-250) antibody
ADRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) antibody
ADRB1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (2nd Extracellular Loop), (AA 200-214) antibody
ADRB1 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (Cy5)
ADRB1 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal Cy5

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (FITC)
ADRB1 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal FITC

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 180-229) antibody
ADRB1 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (Biotin)
ADRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 477 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Wei, Shen, Song, Qiu, Luo: "Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib." in: Oncology reports, Vol. 36, Issue 3, pp. 1576-84, (2016) (PubMed).

Tsai, Lee, Chen, Kao, Lu, Lin, Chen, Chen: "Testosterone replacement increases aged pulmonary vein and left atrium arrhythmogenesis with enhanced adrenergic activity." in: International journal of cardiology, Vol. 176, Issue 1, pp. 110-8, (2014) (PubMed).
抗原

ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

别名

ADRB1 (ADRB1 产品)

背景

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 gene have been shown to affect the resting heart rate and can be involved in heart failure.The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADRB1R, B1AR, BETA1AR, RHR
Protein Interaction Partner: GPRASP1, GPRASP2, SNTA1, ARRB2, ARRB1, MAGI2, DLG4, GRB2, ADRA2A, MAGI3, DLGAP2, GOPC, GIPC1, SH3GL2, SH3GL3, DLG1, NOS1,
Protein Size: 477

分子量

51 kDa

基因ID

153

NCBI登录号

NM_000684, NP_000675

UniProt

P08588

途径

cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation