RNF128 抗体 (C-Term)
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- 抗原 See all RNF128 抗体
- RNF128 (Ring Finger Protein 128 (RNF128))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF128 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128
- Top Product
- Discover our top product RNF128 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 428 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RNF128 (Ring Finger Protein 128 (RNF128))
- 别名
- RNF128 (RNF128 产品)
- 别名
- rnf128 antibody, wu:fb57h05 antibody, zgc:77843 antibody, 1300002C13Rik antibody, AI987883 antibody, GRAIL antibody, Greul1 antibody, RGD1566282 antibody, grail antibody, greul1 antibody, ring finger protein 128a antibody, ring finger protein 128, E3 ubiquitin protein ligase antibody, ring finger protein 128 antibody, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antibody, rnf128a antibody, RNF128 antibody, Rnf128 antibody, rnf128.L antibody
- 背景
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RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ23516, GRAIL
Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
Protein Size: 428 - 分子量
- 47 kDa
- 基因ID
- 79589
- NCBI登录号
- NM_194463, NP_919445
- UniProt
- Q8TEB7
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