MARCH5 抗体 (N-Term)
(1 reference)-
- 抗原 See all MARCH5 抗体
- MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 兔, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARCH5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CRGSTKWVHQ ACLQRWVDEK QRGNSTARVA CPQCNAEYLI VFPKLGPVVY
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MARCH5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH5
- Top Product
- Discover our top product MARCH5 Primary Antibody
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anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 1-95) antibody
MARCH5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 1-95) antibodyMARCH5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (C-Term) antibodyMARCH5 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 小鸡, 兔, 犬, 豚鼠, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 4-32), (N-Term) antibodyMARCH5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21862 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 278 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy." in: Biochimica et biophysica acta, Vol. 1843, Issue 7, pp. 1295-307, (2014) (PubMed).
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: "Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy." in: Biochimica et biophysica acta, Vol. 1843, Issue 7, pp. 1295-307, (2014) (PubMed).
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- 抗原
- MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))
- 别名
- MARCH5 (MARCH5 产品)
- 别名
- march5 antibody, MARCH5 antibody, mitol antibody, rnf153 antibody, march-v antibody, zgc:162966 antibody, MARCH-V antibody, Mar-05 antibody, MITOL antibody, RNF153 antibody, 1810015H18Rik antibody, 2310008I22Rik antibody, 2700055A20Rik antibody, 5730499H23Rik antibody, E130202O05Rik antibody, Marchv antibody, Rnf153 antibody, membrane-associated ring finger (C3HC4) 5 antibody, membrane associated ring-CH-type finger 5 antibody, membrane associated ring-CH-type finger 5 L homeolog antibody, march5 antibody, MARCH5 antibody, march5.L antibody, March5 antibody
- 背景
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MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L). MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896
Alias Symbols: FLJ20445, MARCH-V, MITOL, RNF153
Protein Interaction Partner: FATE1, UBE2W, UBC, DNM1L, MFN2, UBE2E1, FIS1, UBE2E3, MFN1, PARK2, MARCH5, CCNB1, UBE2D3, UBE2D2, UBE2D1, MAP1B, KIAA0368, SOD1, MAVS, TANK, TRAF6, AKTIP, UBE2T, UBE2N, UBE2I, UTRN,
Protein Size: 278 - 分子量
- 31 kDa
- 基因ID
- 54708
- NCBI登录号
- NM_017824, NP_060294
- UniProt
- Q9NX47
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