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RNF43 抗体 (Middle Region)

RNF43 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774743
发货至: 中国
  • 抗原 See all RNF43 抗体
    RNF43 (Ring Finger Protein 43 (RNF43))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 兔, 犬, 马
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF43 antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DFDPLVYCSP KGDPQRVDMQ PSVTSRPRSL DSVVPTGETQ VSSHVHYHRH
    预测反应
    Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against RNF43. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RNF43
    Top Product
    Discover our top product RNF43 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 783 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sugiura, Yamaguchi, Miyamoto: "A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95." in: Experimental cell research, Vol. 314, Issue 7, pp. 1519-28, (2008) (PubMed).

  • 抗原
    RNF43 (Ring Finger Protein 43 (RNF43))
    别名
    RNF43 (RNF43 产品)
    背景
    RNF43 is a HAP95 (AKAP8L) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer.
    Alias Symbols: DKFZp781H02126, DKFZp781H0392, FLJ20315, MGC125630, RNF124, URCC
    Protein Interaction Partner: RSPO1, SFPQ, NONO, HECW1, TP53, UBE2D4, KDM5B, UBE2E3, UBE2N, UBE2E1, UBE2D3, UBE2D2, UBE2D1, AKAP8L, UBC,
    Protein Size: 783
    分子量
    86 kDa
    基因ID
    54894
    NCBI登录号
    NM_017763, NP_060233
    UniProt
    Q68DV7
    途径
    WNT signaling
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