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HERC5 抗体 (Middle Region)

HERC5 适用: 人, Cow, 大鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774739
发货至: 中国
  • 抗原 See all HERC5 抗体
    HERC5 (Hect Domain and RLD 5 (HERC5))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Cow, 大鼠, 马, 兔, Pig
    宿主
    • 12
    • 1
    克隆类型
    • 13
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    This HERC5 antibody is un-conjugated
    应用范围
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    FHPEELKDVI VGNTDYDWKT FEKNARYEPG YNSSHPTIVM FWKAFHKLTL
    预测反应
    Cow: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against HERC5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human HERC5
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1024 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    HERC5 (Hect Domain and RLD 5 (HERC5))
    别名
    HERC5 (HERC5 产品)
    别名
    HERC5 antibody, CEB1 antibody, CEBP1 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antibody, hect domain and RLD 5 antibody, HERC5 antibody
    背景
    HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
    Alias Symbols: CEB1, CEBP1
    Protein Interaction Partner: UBC, SMAD4, UBE2D1, gag, ISG15, TXNRD1, IRF3, HSPA8, CTNNB1, HERC5, SIRT7, STK38, PITX2, ERCC2, CCND1, CCNE1, CCNB1, CCNA2, NME2, CDKN1A,
    Protein Size: 1024
    分子量
    117 kDa
    基因ID
    51191
    NCBI登录号
    NM_016323, NP_057407
    UniProt
    Q69G20
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