UBR2 抗体 (C-Term)
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- 抗原 See all UBR2 抗体
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QGLRRGNPLH LCKERFKKIQ KLWHQHSVTE EIGHAQEANQ TLVGIDWQHL
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against UBR2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human UBR2
- Top Product
- Discover our top product UBR2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1755 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- 别名
- UBR2 (UBR2 产品)
- 别名
- ba49a4.1 antibody, si:ch211-239i4.2 antibody, C6orf133 antibody, RP3-392M17.3 antibody, bA49A4.1 antibody, dJ242G1.1 antibody, dJ392M17.3 antibody, 9930021A08Rik antibody, AI462103 antibody, AW540746 antibody, E130209G04Rik antibody, mKIAA0349 antibody, ubiquitin protein ligase E3 component n-recognin 2 antibody, ubiquitin protein ligase E3 component n-recognin 2 S homeolog antibody, UBR2 antibody, ubr2 antibody, ubr2.S antibody, Ubr2 antibody
- 背景
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Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM].
Alias Symbols: C6orf133, DKFZp686C08114, KIAA0349, MGC71112, RP3-392M17.3, bA49A4.1, dJ242G1.1, dJ392M17.3
Protein Interaction Partner: vif, UBC, UBE2H, RECQL4, HIST1H2BG, HIST2H2AC, TIRAP, UBE2Z, UBXN1, UBXN7, FAF2, FAF1, UBE2B, MYC, HNRNPA1,
Protein Size: 1755 - 分子量
- 200 kDa
- 基因ID
- 23304
- NCBI登录号
- NM_015255, NP_056070
- UniProt
- Q8IWV8
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