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FBXW11 抗体 (N-Term)

FBXW11 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774702
发货至: 中国
  • 抗原 See all FBXW11 抗体
    FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 26
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼
    宿主
    • 24
    • 2
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This FBXW11 antibody is un-conjugated
    应用范围
    • 21
    • 18
    • 16
    • 13
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    CLQSMPSVRC LQISNGTSSV IVSRKRPSEG NYQKEKDLCI KYFDQWSESD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against FBXW11. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human FBXW11
    Top Product
    Discover our top product FBXW11 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 542 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
    别名
    FBXW11 (FBXW11 产品)
    别名
    BTRC2 antibody, BTRCP2 antibody, FBW1B antibody, FBXW1B antibody, Fbw11 antibody, Hos antibody, 2310065A07Rik antibody, AA536858 antibody, Fbxw1b antibody, HOS antibody, btrc2 antibody, fbxw11a antibody, wu:fa12e12 antibody, wu:fb11f03 antibody, zgc:63728 antibody, fbxw11 antibody, fbxw11b antibody, fbxw1b antibody, wu:fd14d12 antibody, wu:fi43f07 antibody, F-box and WD repeat domain containing 11 antibody, F-box and WD-40 domain protein 11 antibody, F-box/WD repeat-containing protein 11 antibody, F-box and WD repeat domain containing 11b antibody, F-box and WD repeat domain containing 11a antibody, FBXW11 antibody, Fbxw11 antibody, LOC100199403 antibody, fbxw11b antibody, fbxw11a antibody
    背景
    FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
    Alias Symbols: BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
    Protein Interaction Partner: ELMO2, NCKAP5L, USP37, CACHD1, ZNF395, TACC1, STK4, STK3, SKP1, REST, RELA, RAP1GAP, PFDN5, PFDN4, NRD1, NFKB2, NFKB1, NFE2L2, NEDD8, MAX, LRCH4, ILF3, FOXN2, HNRNPU, HIVEP2, HIVEP1, HCFC1, EZH2, DOCK1, DHX9, CTNNB1, CTNNA1, CLTC, CHD1, CDC34, CDC25B, CDC
    Protein Size: 542
    分子量
    62 kDa
    基因ID
    23291
    NCBI登录号
    NM_012300, NP_036432
    UniProt
    Q9UKB1
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