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- 抗原 See all FBXO5 抗体
- FBXO5 (F-Box Protein 5 (FBXO5))
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抗原表位
- C-Term
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适用
- 人, 犬, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXO5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ASVQKSAAQT SLKKDAQTKL SNQGDQKGST YSRHNEFSEV AKTLKKNESL
- 预测反应
- Dog: 85%, Human: 100%, Pig: 79%, Rabbit: 92%
- 产品特性
- This is a rabbit polyclonal antibody against FBXO5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human FBXO5
- Top Product
- Discover our top product FBXO5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 447 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles." in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007) (PubMed).
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Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles." in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007) (PubMed).
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- 抗原
- FBXO5 (F-Box Protein 5 (FBXO5))
- 别名
- FBXO5 (FBXO5 产品)
- 别名
- EMI1 antibody, FBX5 antibody, Fbxo31 antibody, 2510044I10Rik antibody, C85305 antibody, Emi1 antibody, emi1 antibody, fc65h02 antibody, wu:fc65h02 antibody, wu:fe06e07 antibody, wu:fz79f03 antibody, zgc:136397 antibody, zgc:158541 antibody, fbx5 antibody, Fbxo5 antibody, ACYPI007854 antibody, fbxo5 antibody, F-box protein 5 antibody, F-box only protein 5 antibody, F-box protein 5 L homeolog antibody, F-box protein 5 S homeolog antibody, FBXO5 antibody, Fbxo5 antibody, fbxo5 antibody, fbxo5.L antibody, fbxo5.S antibody
- 背景
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FBXO5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class and is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EMI1, FBX5, Fbxo31
Protein Interaction Partner: FBXW11, UBE2S, SKP1, UBC, TPM3, NEDD8, BRCA1, BARD1, ANAPC1, ANAPC11, ANAPC7, ANAPC5, FZR1, ANAPC4, ANAPC2, CDC16, CDC23, CDC27, CDC20, CDK1, MYC, Gm9174, BTRC, PLK1, EVI5,
Protein Size: 447 - 分子量
- 50 kDa
- 基因ID
- 26271
- NCBI登录号
- NM_012177, NP_036309
- UniProt
- Q9UKT4
- 途径
- Mitotic G1-G1/S Phases
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