THOC7 抗体 (C-Term)
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- 抗原 See all THOC7 抗体
- THOC7 (THO Complex 7 (THOC7))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This THOC7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ELEHLSHIKE SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
- 产品特性
- This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7
- Top Product
- Discover our top product THOC7 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 204 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- THOC7 (THO Complex 7 (THOC7))
- 别名
- THOC7 (THOC7 产品)
- 别名
- RGD1305475 antibody, NIF3L1BP1 antibody, fSAP24 antibody, 1500006O09Rik antibody, 9230101K24Rik antibody, Nif3l1bp1 antibody, THO complex 7 antibody, Thoc7 antibody, THOC7 antibody
- 背景
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THOC7 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.
Alias Symbols: FLJ23445, NIF3L1BP1, fSAP24
Protein Interaction Partner: THOC2, RPA3, RPA2, RPA1, CKAP4, UBC, ZC3H15, TRMT112, PPIP5K2, THOC1, UBE3C, USP13, ZPR1, THOC5, VIM, S100A13, WDR36, ZCRB1, THOC3, ZNF606, THOC6, ALYREF, DDX39B, NIF3L1, CHD3, MED8, GOT2, MED18, MED22,
Protein Size: 204 - 分子量
- 22 kDa
- 基因ID
- 80145
- NCBI登录号
- NM_025075, NP_079351
- UniProt
- Q6I9Y2
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