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Adenylosuccinate Lyase 抗体 (Middle Region)

ADSL 适用: 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马, Cow, Pig, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774275
发货至: 中国
  • 抗原 See all Adenylosuccinate Lyase (ADSL) 抗体
    Adenylosuccinate Lyase (ADSL)
    抗原表位
    • 15
    • 10
    • 3
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马, Cow, Pig, 绵羊
    宿主
    • 40
    • 4
    克隆类型
    • 41
    • 2
    多克隆
    标记
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This Adenylosuccinate Lyase antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RVRDDLRFRG VKGTTGTQAS FLQLFEGDDH KVEQLDKMVT EKAGFKRAFI
    预测反应
    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 93%
    产品特性
    This is a rabbit polyclonal antibody against ADSL. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ADSL
    Top Product
    Discover our top product ADSL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 484 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Adenylosuccinate Lyase (ADSL)
    别名
    ADSL (ADSL 产品)
    别名
    fi60b04 antibody, zgc:56061 antibody, wu:fi60b04 antibody, MGC53383 antibody, MGC69239 antibody, adsL antibody, F15C21.8 antibody, F15C21_8 antibody, AMPS antibody, ASASE antibody, ASL antibody, Adl antibody, Asl antibody, purB antibody, adenylosuccinate lyase antibody, adenylosuccinate lyase L homeolog antibody, adenylosuccinase; ASL antibody, Adenylosuccinate lyase antibody, L-Aspartase-like family protein antibody, ADSL antibody, adsl antibody, adsl.L antibody, ASL antibody, purB antibody, purB,adsL antibody, Mrub_2293 antibody, MMAH_RS02975 antibody, Arnit_0089 antibody, Mesil_1058 antibody, Slip_0597 antibody, Trad_2452 antibody, Deba_0652 antibody, Toce_1174 antibody, Acear_2324 antibody, Igag_0272 antibody, Saut_2156 antibody, Fbal_1996 antibody, Ndas_2434 antibody, Ilyop_0196 antibody, Lbys_2961 antibody, MFER_RS02920 antibody, Palpr_2192 antibody, Calni_0061 antibody, Ftrac_3746 antibody, AT1G36280 antibody, Olsu_1764 antibody, Adsl antibody
    背景
    Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: AMPS, ASASE, ASL
    Protein Interaction Partner: CALCOCO2, REL, UBC, PDE12, BTF3L4, NPLOC4, EHD4, UBQLN2, NT5C2, WDR4, PAIP1, PLIN3, SAE1, OXSR1, API5, XPNPEP1, WARS, RAD23B, TWF1, DNAJB1, GTF2I, EIF1AX, DRG2, CTSC, NOV, TYMS, SUMO1, DDA1, USP15, USP4,
    Protein Size: 484
    分子量
    55 kDa
    基因ID
    158
    NCBI登录号
    NM_000026, NP_000017
    UniProt
    P30566
    途径
    Ribonucleoside Biosynthetic Process
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