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COPS4 抗体 (Middle Region)

COPS4 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774165
发货至: 中国
  • 抗原 See all COPS4 抗体
    COPS4 (COP9 Signalosome Subunit 4 (COPS4))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 24
    • 22
    • 21
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS4 antibody is un-conjugated
    应用范围
    • 24
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    YKLETYLKIA RLYLEDDDPV QAEAYINRAS LLQNESTNEQ LQIHYKVCYA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against COPS4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human COPS4
    Top Product
    Discover our top product COPS4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 406 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    COPS4 (COP9 Signalosome Subunit 4 (COPS4))
    别名
    COPS4 (COPS4 产品)
    背景
    COPS4 is one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC10899, MGC15160, CSN4
    Protein Interaction Partner: USHBP1, GPS1, UBC, Skp2, PRMT5, KPNA2, HSP90AB1, EPB41L2, EPB41L1, CAST, WDR77, ENAH, DCAF8, COPS5, STIP1, COPS6, YWHAQ, FOS, COPS8, COPS7A, FBXO6, BAG3, FBXW4, vpr, IRF5, COPS7B, COPS2, COPS3, TOR1AIP2, LRR1, FBXO17, DCAF11, DDA1, RFWD2, KLHL42, GRK5, DD
    Protein Size: 406
    分子量
    46 kDa
    基因ID
    51138
    NCBI登录号
    NM_016129, NP_057213
    UniProt
    Q9BT78
    途径
    Cell Division Cycle
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