HSPB8 抗体 (Middle Region)
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- 抗原 See all HSPB8 抗体
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 山羊, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSPB8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against HSPB8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HSPB8
- Top Product
- Discover our top product HSPB8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 196 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- 别名
- HSPB8 (HSPB8 产品)
- 别名
- CMT2L antibody, DHMN2 antibody, E2IG1 antibody, H11 antibody, HMN2 antibody, HMN2A antibody, HSP22 antibody, MGC64408 antibody, hsc70 antibody, wu:fb01g06 antibody, wu:fi48b06 antibody, fc09c11 antibody, wu:fc04b04 antibody, wu:fc09c11 antibody, zgc:64202 antibody, AU018630 antibody, AW413033 antibody, Cryac antibody, D5Ucla4 antibody, H11K antibody, HSP20-like antibody, Hsp22 antibody, heat shock protein family B (small) member 8 antibody, heat shock protein family B (small) member 8 L homeolog antibody, heat shock protein 8 antibody, heat shock protein b8 antibody, HSPB8 antibody, hspb8.L antibody, hspa8 antibody, hspb8 antibody, Hspb8 antibody
- 背景
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HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alias Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Protein Interaction Partner: QRICH1, HSPB7, DUSP12, BAG3, ASB4, UBC, CIAPIN1, DSTN, HSPB6, HSPB3, SNCA, CRYAB, HSPB1, HSPB8, MAPK3, PRKCA, CSNK2A1, HSPB2,
Protein Size: 196 - 分子量
- 21 kDa
- 基因ID
- 26353
- NCBI登录号
- NM_014365, NP_055180
- UniProt
- Q9UJY1
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