TMC8 抗体 (N-Term)
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- 抗原 See all TMC8 抗体
- TMC8 (Transmembrane Channel-Like 8 (TMC8))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TMC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PGPTLNLTLQ CPGSRQSPPG VLRFHNQLWH VLTGRAFTNT YLFYGAYRVG
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TMC8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TMC8
- Top Product
- Discover our top product TMC8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 726 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TMC8 (Transmembrane Channel-Like 8 (TMC8))
- 别名
- TMC8 (TMC8 产品)
- 别名
- EV2 antibody, EVER2 antibody, EVIN2 antibody, Ever2 antibody, mFLJ00400 antibody, transmembrane channel like 8 antibody, transmembrane channel-like 8 antibody, transmembrane channel-like gene family 8 antibody, TMC8 antibody, Tmc8 antibody
- 背景
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Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs.
Alias Symbols: EV2, EVER2, EVIN2, MGC102701, MGC40121
Protein Interaction Partner: TRAF2, TRAF1,
Protein Size: 726 - 分子量
- 82 kDa
- 基因ID
- 147138
- NCBI登录号
- NM_152468, NP_689681
- UniProt
- Q8IU68
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