OAS1 抗体 (Middle Region)
(2 references)-
- 抗原 See all OAS1 抗体
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OAS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- RRQLTKPRPV ILDPADPTGN LGGGDPKGWR QLAQEAEAWL NYPCFKNWDG
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against OAS1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human OAS1
- Top Product
- Discover our top product OAS1 Primary Antibody
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anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 139-358) antibodyOAS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 302-330), (C-Term) antibodyOAS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1937 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibodyOAS1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 296-395) antibodyOAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) antibodyOAS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) antibodyOAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 324-373) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (N-Term) antibodyOAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 414 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells." in: Immunology and cell biology, Vol. 92, Issue 2, pp. 105-15, (2014) (PubMed).
: "RIG-I-like receptors mediate innate antiviral response in mouse testis." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1455-67, (2013) (PubMed).
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: "Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells." in: Immunology and cell biology, Vol. 92, Issue 2, pp. 105-15, (2014) (PubMed).
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- 抗原
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- 别名
- OAS1 (OAS1 产品)
- 别名
- OAS1 antibody, IFI-4 antibody, OIAS antibody, OIASI antibody, L3 antibody, Pp2a2 antibody, 2',5'-oligoadenylate synthetase 1 antibody, 2'-5'-oligoadenylate synthetase 1 antibody, 2'-5' oligoadenylate synthetase 1A antibody, protein phosphatase 2 catalytic subunit beta antibody, OAS1 antibody, Oas1a antibody, Ppp2cb antibody, Oas1 antibody
- 背景
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This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: IFI-4, OIAS, OIASI
Protein Interaction Partner: EXOC5, TRIM27, ACTN1, PRMT6, WBSCR22, RPL30, HCVgp1,
Protein Size: 414 - 分子量
- 47 kDa
- 基因ID
- 4938
- NCBI登录号
- NM_001032409, NP_001027581
- 途径
- Hepatitis C
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