NPRL2 抗体 (N-Term)
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- 抗原 See all NPRL2 抗体
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPRL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TUSC4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TUSC4
- Top Product
- Discover our top product NPRL2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 380 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- 抗原
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
- 别名
- TUSC4 (NPRL2 产品)
- 别名
- 2810446G01Rik antibody, G21 antibody, NPR2L antibody, Tusc4 antibody, npr2 antibody, npr2l antibody, tusc4 antibody, NPR2 antibody, TUSC4 antibody, im:6900399 antibody, zgc:153630 antibody, nitrogen permease regulator-like 2 antibody, NPR2 like, GATOR1 complex subunit S homeolog antibody, NPR2 like, GATOR1 complex subunit antibody, NPR2-like, GATOR1 complex subunit antibody, Nprl2 antibody, nprl2.S antibody, NPRL2 antibody, nprl2 antibody
- 背景
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TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Alias Symbols: NPR2L, NPRL2, NPR2, TUSC4
Protein Interaction Partner: UBC, HSP90AA1, CDKN1A, ANXA7, NPRL3, UBE2M, PRKAR1A,
Protein Size: 380 - 分子量
- 44 kDa
- 基因ID
- 10641
- NCBI登录号
- NM_006545, NP_006536
- UniProt
- Q8WTW4
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