PRTFDC1 抗体 (Middle Region)
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- 抗原 See all PRTFDC1 抗体
- PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
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抗原表位
- Middle Region
- 适用
- 人, 大鼠, Pig, 马, 兔, 斑马鱼, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRTFDC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MKALLSNIEK YKPNMIKVAS LLVKRTSRSD GFRPDYAGFE IPNLFVVGYA
- 预测反应
- Dog: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 77%, Rat: 92%, Zebrafish: 77%
- 产品特性
- This is a rabbit polyclonal antibody against PRTFDC1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRTFDC1
- Top Product
- Discover our top product PRTFDC1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 225 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).
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PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).
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- 抗原
- PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
- 别名
- PRTFDC1 (PRTFDC1 产品)
- 别名
- HHGP antibody, HPRT antibody, hprt1 antibody, hprt1l antibody, zgc:55561 antibody, zgc:86771 antibody, MGC80959 antibody, OTTMUSG00000011667 antibody, Prtfdc1 antibody, phosphoribosyl transferase domain containing 1 antibody, phosphoribosyl transferase domain containing 1 L homeolog antibody, phosphoribosyltransferase domain containing 1 pseudogene antibody, PRTFDC1 antibody, prtfdc1 antibody, Prtfdc1 antibody, prtfdc1.L antibody, Gm13377 antibody
- 背景
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PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.
Alias Symbols: FLJ11888, HHGP
Protein Interaction Partner: LGALS9B, EEF2KMT, MCMBP, GNPDA1, EPM2AIP1, TCL1A, HPRT1, UBC, RTN3, FLAD1, NIF3L1, DTNB, STAT5A, EWSR1,
Protein Size: 225 - 分子量
- 26 kDa
- 基因ID
- 56952
- NCBI登录号
- NM_020200, NP_064585
- UniProt
- Q9NRG1
- 途径
- Ribonucleoside Biosynthetic Process
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