SEPN1 抗体 (C-Term)
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- 抗原 See all SEPN1 抗体
- SEPN1 (Selenoprotein N, 1 (SEPN1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, Cow, 豚鼠, 马, 大鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SEPN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ANYFLDITSV KPEEIESNLF SFSSTFEDPS TATYMQFLKE GLRRGLPLLQ
- 预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against SEPN1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SEPN1
- Top Product
- Discover our top product SEPN1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 590 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SEPN1 (Selenoprotein N, 1 (SEPN1))
- 别名
- SEPN1 (SEPN1 产品)
- 别名
- CFTD antibody, MDRS1 antibody, RSMD1 antibody, RSS antibody, SELN antibody, 1110019I12Rik antibody, AI414492 antibody, SePN antibody, cb686 antibody, wu:fb06g01 antibody, wu:fb73d02 antibody, wu:fv41b08 antibody, zgc:101091 antibody, selenoprotein N antibody, SELENON antibody, Selenon antibody, selenon antibody
- 背景
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SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: FLJ24021, MDRS1, RSMD1, RSS, SELN, CFTD
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 590 - 分子量
- 62 kDa
- 基因ID
- 57190
- NCBI登录号
- NM_020451, NP_065184
- UniProt
- Q9NZV5
- 途径
- Skeletal Muscle Fiber Development
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