SEC63 抗体 (C-Term)
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- 抗原 See all SEC63 抗体
- SEC63 (SEC63 Homolog (SEC63))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 斑马鱼, Cow, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SEC63 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- WWLYIADRKE QTLISMPYHV CTLKDTEEVE LKFPAPGKPG NYQYTVFLRS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against SEC63. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SEC63
- Top Product
- Discover our top product SEC63 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 760 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SEC63 (SEC63 Homolog (SEC63))
- 别名
- SEC63 (SEC63 产品)
- 别名
- DNAJC23 antibody, ERdj2 antibody, PRO2507 antibody, SEC63L antibody, 5730478J10Rik antibody, AI649014 antibody, AW319215 antibody, SEC63-like antibody, zgc:92718 antibody, SEC63 homolog, protein translocation regulator antibody, SEC63-like (S. cerevisiae) antibody, SEC63 homolog, protein translocation regulator L homeolog antibody, SEC63 antibody, Sec63 antibody, sec63 antibody, sec63.L antibody
- 背景
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: ERdj2, PRO2507, SEC63L, DNAJC23
Protein Interaction Partner: UBC, IRF1, SEC61B, SEC62, GSTK1,
Protein Size: 760 - 分子量
- 88 kDa
- 基因ID
- 11231
- NCBI登录号
- NM_007214, NP_009145
- UniProt
- Q9UGP8
- 途径
- ER-Nucleus Signaling
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