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- 抗原 See all C1QB 抗体
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
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抗原表位
- C-Term
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适用
- 人, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C1QB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS IFSGFLLFPD
- 预测反应
- Dog: 92%, Horse: 82%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human C1QB
- Top Product
- Discover our top product C1QB Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 253 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Histopathological comparison of the onset of peri-implantitis and periodontitis in rats." in: Clinical oral implants research, Vol. 28, Issue 2, pp. 163-170, (2016) (PubMed).
: "The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium." in: Journal of periodontal research, Vol. 52, Issue 1, pp. 74-82, (2016) (PubMed).
: "Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats." in: Journal of periodontal research, Vol. 49, Issue 3, pp. 314-22, (2014) (PubMed).
: "Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction." in: Journal of periodontal research, Vol. 48, Issue 4, pp. 420-7, (2013) (PubMed).
: "The formation of immune complexes is involved in the acute phase of periodontal destruction in rats." in: Journal of periodontal research, Vol. 47, Issue 4, pp. 455-62, (2012) (PubMed).
: "Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide." in: Journal of periodontal research, Vol. 47, Issue 5, pp. 674-80, (2012) (PubMed).
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Histopathological comparison of the onset of peri-implantitis and periodontitis in rats." in: Clinical oral implants research, Vol. 28, Issue 2, pp. 163-170, (2016) (PubMed).
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- 抗原
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- 别名
- C1QB (C1QB 产品)
- 别名
- complement C1q B chain antibody, complement component 1, q subcomponent, beta polypeptide antibody, C1QB antibody, C1qb antibody
- 背景
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C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.
Alias Symbols: -
Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
Protein Size: 253 - 分子量
- 27 kDa
- 基因ID
- 713
- NCBI登录号
- NM_000491, NP_000482
- UniProt
- P02746
- 途径
- Complement System
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