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PRP19 抗体 (Middle Region)

PRPF19 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2773819
发货至: 中国
  • 抗原 See all PRP19 (PRPF19) 抗体
    PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
    抗原表位
    • 10
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 64
    • 51
    • 34
    • 9
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠
    宿主
    • 61
    • 3
    克隆类型
    • 54
    • 10
    多克隆
    标记
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    This PRP19 antibody is un-conjugated
    应用范围
    • 45
    • 30
    • 25
    • 14
    • 9
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    PSVVGAGEPM DLGELVGMTP EIIQKLQDKA TVLTTERKKR GKTVPEELVK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against PRPF19. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PRPF19
    Top Product
    Discover our top product PRPF19 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 504 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Song, Cui, Zhong, Han: "Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium." in: Journal of clinical pathology, Vol. 62, Issue 9, pp. 802-7, (2009) (PubMed).

  • 抗原
    PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
    别名
    PRPF19 (PRPF19 产品)
    别名
    NMP200 antibody, fb18f09 antibody, zgc:56158 antibody, wu:fb18f09 antibody, nmp200 antibody, PRP19 antibody, PSO4 antibody, SNEV antibody, UBOX4 antibody, hPSO4 antibody, Prp19 antibody, nmp-200 antibody, AA617263 antibody, AL024362 antibody, D19Wsu55e antibody, Snev antibody, pre-mRNA processing factor 19 antibody, pre-mRNA processing factor 19 L homeolog antibody, prpf19 antibody, prpf19.L antibody, PRPF19 antibody, Prpf19 antibody
    背景
    PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM].
    Alias Symbols: NMP200, PRP19, PSO4, UBOX4, hPSO4, SNEV
    Protein Interaction Partner: HUWE1, USP4, UBE2D3, SUMO2, CEP76, CEP250, TUBGCP3, CEP57, VCP, UBC, SUMO1, NEDD8, LIN28A, EXOC7, EXOC3, RPA3, RPA2, RPA1, RNF2, SUZ12, EED, rev, MEPCE, SEC13, PARK2, TARDBP, UBD, CSNK2A2, UCHL5, WHSC1, U2AF1, PRCC, HSP90AA1, HSPB1, FN1, RBM10, vif, CDC40
    Protein Size: 504
    分子量
    55 kDa
    基因ID
    27339
    NCBI登录号
    NM_014502, NP_055317
    UniProt
    Q9UMS4
    途径
    Ribonucleoprotein Complex Subunit Organization
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