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OTC 抗体 (N-Term)

Name: OTC 抗体 (N-Term)
SKU: ABIN2773791
Availability: OutOfStock

OTC 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 绵羊, 兔, 山羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-OTC Antibody Titration: 2. (OTC 抗体 (N-Term))

Rabbit Anti-OTC Antibody Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4. (OTC 抗体 (N-Term))

IHC

Host: Rabbit Target Name: OTC Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1. (OTC 抗体 (N-Term))

Host: Rabbit Target Name: OTC Sample Tissue: Human HepG2 Antibody Dilution: 1. (OTC 抗体 (N-Term))

4 images

(4 references)

产品编号 ABIN2773791

发货至: 中国

Datasheet as PDF

抗原 See all OTC 抗体

OTC (Ornithine Carbamoyltransferase (OTC))
抗原表位
15

11

8

3

2

1

1

1

1

1

1

1

1
N-Term
适用
36

30

23

5

3

3

3

2

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 绵羊, 兔, 山羊, 豚鼠
宿主
47

7
兔
Compatible Secondaries
克隆类型
47

7
多克隆
标记
25

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This OTC antibody is un-conjugated
应用范围
43

16

14

13

13

10

8

4

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

AFRNGHNFMV RNFRCGQPLQ NKVQLKGRDL LTLKNFTGEE IKYMLWLSAD

预测反应

Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against OTC. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human OTC

Top Product

Discover our top product OTC Primary Antibody
anti-Ornithine Carbamoyltransferase (OTC) (AA 78-129) antibody
OTC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (AA 215-354) antibody
OTC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) antibody
OTC 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (AA 51-150) antibody
OTC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (AA 33-354) antibody
OTC 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (N-Term) antibody
OTC 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 绵羊, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (N-Term) antibody
OTC 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (AA 71-98) antibody
OTC 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21474 unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (AA 71-98) antibody
OTC 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Ornithine Carbamoyltransferase (OTC) (AA 31-130) antibody
OTC 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 354 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hallows, Yu, Smith, Devries, Devires, Ellinger, Someya, Shortreed, Prolla, Markley, Smith, Zhao, Guan, Denu: "Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction." in: Molecular cell, Vol. 41, Issue 2, pp. 139-49, (2011) (PubMed).

Walters, Wallace: "Urea cycle gene expression is suppressed by PFOA treatment in rats." in: Toxicology letters, Vol. 197, Issue 1, pp. 46-50, (2010) (PubMed).

Yu, Lin, Yao, Huang, Lei, Xiong, Zhao, Guan: "Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13669-75, (2009) (PubMed).

Tanaka, Wada, Maruyama, Tanaka, Takikawa, Komatsu: "Hyperammonemia-induced encephalopathy due to ornithine transcarbamylase deficiency in an adult woman: identification of novel missense mutations." in: Journal of gastroenterology, Vol. 40, Issue 1, pp. 106-7, (2005) (PubMed).
抗原

OTC (Ornithine Carbamoyltransferase (OTC))

别名

OTC (OTC 产品)

别名

OCTD antibody, 2810428A13Rik antibody, AA589422 antibody, AW457381 antibody, OCT antibody, Plxn2 antibody, mKIAA0463 antibody, F1B16.13 antibody, F1B16_13 antibody, ORNITHINE CARBAMOYLTRANSFERASE antibody, ornithine carbamoyltransferase antibody, BA4351 antibody, PSPTO4164 antibody, PLXN2 antibody, AI265390 antibody, Sf antibody, spf antibody, si:dkey-19h21.3 antibody, ornithine carbamoyltransferase antibody, plexin A2 antibody, ornithine carbamoyltransferase ArgF antibody, ornithine transcarbamylase antibody, OTC antibody, Plxna2 antibody, Otc antibody, argF antibody, argF-2 antibody, atpD-2 antibody, CNC04300 antibody, PLXNA2 antibody, otc antibody

背景

OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Alias Symbols: OCTD
Protein Interaction Partner: OTC, TOMM20,
Protein Size: 354

分子量

39 kDa

基因ID

5009

NCBI登录号

NM_000531, NP_000522

UniProt

P00480