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PDE4A 抗体

PDE4A 适用: 人, 小鼠, 大鼠, Elk WB, IHC, ELISA, IF, IP, ICC, CM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2750880
发货至: 中国
  • 抗原 See all PDE4A 抗体
    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
    适用
    • 57
    • 34
    • 26
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    人, 小鼠, 大鼠, Elk
    宿主
    • 50
    • 7
    克隆类型
    • 52
    • 5
    多克隆
    标记
    • 19
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE4A antibody is un-conjugated
    应用范围
    • 49
    • 20
    • 13
    • 13
    • 12
    • 6
    • 6
    • 6
    • 5
    • 4
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)
    纯化方法
    Affinity Purified
    免疫原
    Synthetic cyclic peptide common to all PDE4A proteins.
    亚型
    IgG
    Top Product
    Discover our top product PDE4A Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.65-1.00 μg/μL
  • Avila, Barker, Zhang, McClain, Barve, Gobejishvili: "Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis." in: The Journal of pathology, Vol. 240, Issue 1, pp. 96-107, (2017) (PubMed).

    Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

    Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

    Kedia, Ückert, Oelke, Sonnenberg, Sohn, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).

    Yougbaré, Boire, Roy, Lugnier, Rouseau: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).

    Guo, Lin, Zhao, Zhang, Wei, Wang, Wang: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." in: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).

    Zhai, Chang, Wei, Liu, Leblais, Fischmeister, Ji: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).

    Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

    Ückert, Waldkirch, Sonnenberg, Sandner, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." in: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).

    Waldkirch, Ückert, Sigl, Satzger, Geismar, Langnäse, Richter, Sohn, Kuczyk, Hedlund: "Expression of cyclic AMP-dependent protein kinase isoforms in human cavernous arteries: functional significance and relation to phosphodiesterase type 4." in: The journal of sexual medicine, Vol. 7, Issue 6, pp. 2104-2111, (2011) (PubMed).

    Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

    Yougbare, Morin, Senouvo, Sirois, Albadine, Lugnier, Rousseau: "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 4, pp. L441-50, (2011) (PubMed).

    Vedin, Eriksson, Berghard: "Organization of the chemosensory neuroepithelium of the vomeronasal organ of the Scandinavian moose Alces alces." in: Brain research, Vol. 1306, pp. 53-61, (2010) (PubMed).

    Fatemi, Folsom, Reutiman, Braun, Lavergne: "Levels of phosphodiesterase 4A and 4B are altered by chronic treatment with psychotropic medications in rat frontal cortex." in: Synapse (New York, N.Y.), Vol. 64, Issue 7, pp. 550-5, (2010) (PubMed).

    Waldkirch, Uckert, Sigl, Langnaese, Richter, Stief, Kuczyk, Hedlund: "Expression of cAMP-dependent protein kinase isoforms in the human prostate: functional significance and relation to PDE4." in: Urology, Vol. 76, Issue 2, pp. 515.e8-14, (2010) (PubMed).

    Fatemi, Reutiman, Folsom, Lee: "Phosphodiesterase-4A expression is reduced in cerebella of patients with bipolar disorder." in: Psychiatric genetics, Vol. 18, Issue 6, pp. 282-8, (2009) (PubMed).

    Hörnberg, Gussing, Berghard, Bohm: "Retinoic acid selectively inhibits death of basal vomeronasal neurons during late stage of neural circuit formation." in: Journal of neurochemistry, Vol. 110, Issue 4, pp. 1263-75, (2009) (PubMed).

    Liu, Fraser, Koos: "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." in: The Journal of comparative neurology, Vol. 516, Issue 1, pp. 36-48, (2009) (PubMed).

    Zhang, Huang, Masood, Stolinski, Li, Zhang, Dlaboga, Jin, Conti, ODonnell: "Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B)." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 33, Issue 7, pp. 1611-23, (2008) (PubMed).

    Braun, Reutiman, Lee, Folsom, Fatemi: "Expression of phosphodiesterase 4 is altered in the brains of subjects with autism." in: Neuroreport, Vol. 18, Issue 17, pp. 1841-4, (2008) (PubMed).

  • 抗原
    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
    别名
    PDE4A (PDE4A 产品)
    别名
    pde4 antibody, dpde2 antibody, pde46 antibody, PDE4A antibody, Pde4a antibody, D9Ertd60e antibody, Dpde2 antibody, DPDE2 antibody, PDE4 antibody, PDE46 antibody, PHOSA antibody, phosphodiesterase 4A S homeolog antibody, phosphodiesterase 4A, cAMP-specific antibody, phosphodiesterase 4A antibody, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) antibody, cAMP-specific 3',5'-cyclic phosphodiesterase 4A antibody, phosphodiesterase 4A, cAMP specific antibody, phosphodiesterase 4C antibody, pde4a.S antibody, pde4a antibody, PDE4A antibody, LOC100009247 antibody, Pde4a antibody, PDE4C antibody
    UniProt
    P27815
    途径
    cAMP Metabolic Process
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