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CD24 抗体 (APC)

Name: CD24 抗体 (APC)
Brand: antibodies-online
SKU: ABIN2749227
Availability: OutOfStock

CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 APC

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-human CD24 (SN3) APC. (CD24 抗体 (APC))

FACS

Surface staining of human peripheral blood cells with anti-CD24 (SN3) Alexa Fluor® 700. (CD24 抗体 (APC))

FACS

2 images

(6 references)

产品编号 ABIN2749227

发货至: 中国

Datasheet as PDF

抗原 See all CD24 抗体

CD24 (CD24 Molecule (CD24))
适用
81

73

35

1
人
宿主
57

46

32
小鼠
Compatible Secondaries
克隆类型
78

56

1
单克隆
标记
37

14

13

11

7

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This CD24 antibody is conjugated to APC
应用范围
90

52

27

22

21

16

13

13

6

4

2

2

2

2

1

1
Flow Cytometry (FACS)

特异性

The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.

交叉反应（详细）

Human

纯化方法

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Glycoproteins purified from human NALM-1 cell line.

克隆位点

SN3

亚型

IgG1

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CD24 适用: 人, 小鼠, 大鼠 IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD24 Molecule (CD24) (AA 1-80) antibody
CD24 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-CD24 Molecule (CD24) antibody
CD24 适用: 人 FACS, IHC (fro), CyTOF 宿主: 小鼠 Monoclonal SN3 unconjugated

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CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 PE

anti-CD24 Molecule (CD24) (AA 30-60) antibody
CD24 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

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CD24 适用: 人 FACS, IHC, IHC (fro), IF 宿主: 小鼠 Monoclonal ML5 unconjugated

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CD24 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated

anti-CD24 Molecule (CD24) antibody (PE-DyLight 594)
CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 PE-DyLight 594

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

说明

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Všianská, Říhová, Varmužová, Suská, Kryukov, Mikulášová, Kupská, Penka, Pour, Adam, Hájek: "Analysis of B-cell subpopulations in monoclonal gammopathies." in: Clinical lymphoma, myeloma & leukemia, Vol. 15, Issue 4, pp. e61-71, (2015) (PubMed).

Maliar, Servais, Waks, Chmielewski, Lavy, Altevogt, Abken, Eshhar: "Redirected T cells that target pancreatic adenocarcinoma antigens eliminate tumors and metastases in mice." in: Gastroenterology, Vol. 143, Issue 5, pp. 1375-84.e1-5, (2012) (PubMed).

Solvason, Kearney: "The human fetal omentum: a site of B cell generation." in: The Journal of experimental medicine, Vol. 175, Issue 2, pp. 397-404, (1992) (PubMed).

Fischer, Majdic, Gadd, Knapp: "Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 2, pp. 638-41, (1990) (PubMed).

Barcos, Pollard, Fukukawa, Seon: "Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3." in: Hematological oncology, Vol. 4, Issue 4, pp. 251-9, (1987) (PubMed).

Fukukawa, Matsuzaki, Haruta, Hara, Seon: "New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells." in: Experimental hematology, Vol. 14, Issue 9, pp. 850-5, (1986) (PubMed).
抗原

CD24 (CD24 Molecule (CD24))

别名

CD24 (CD24 产品)

别名

CD24A antibody, Cd24a antibody, CD24 molecule antibody, CD24 antibody, Cd24 antibody

背景

CD24 Molecule,CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.,HSA, nectadorin, SCLC4

基因ID

100133941

UniProt

P25063

途径

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation