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- 抗原 See all IL9 Receptor (IL9R) 抗体
- IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL9 Receptor antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- 免疫原
- Human CD129-transfected cell line
- 克隆位点
- AH9R7
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product IL9R Primary Antibody
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- 应用备注
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Functional application: Blocking.
Flow cytometry: It is recommended to use bright fluorochromes or signal multiplying detection. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).
: "Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1761-7, (2000) (PubMed).
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Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).
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- 抗原
- IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
- 别名
- CD129 / IL-9R alpha (IL9R 产品)
- 别名
- CD129 antibody, IL-9R antibody, interleukin 9 receptor antibody, IL9R antibody, Il9r antibody
- 背景
- Interleukin 9 receptor,CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.,IL9R
- 基因ID
- 3581
- UniProt
- Q01113
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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