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IL9 Receptor 抗体

IL9R 适用: 人 ELISA, FACS, Func 宿主: 小鼠 Monoclonal AH9R7 unconjugated
产品编号 ABIN2749221
发货至: 中国
  • 抗原 See all IL9 Receptor (IL9R) 抗体
    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
    适用
    • 44
    • 18
    • 1
    宿主
    • 34
    • 11
    • 2
    小鼠
    克隆类型
    • 33
    • 13
    • 1
    单克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This IL9 Receptor antibody is un-conjugated
    应用范围
    • 28
    • 25
    • 23
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
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    ELISA, Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    内毒素水平
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    免疫原
    Human CD129-transfected cell line
    克隆位点
    AH9R7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IL9R Primary Antibody
  • 应用备注
    Functional application: Blocking.
    Flow cytometry: It is recommended to use bright fluorochromes or signal multiplying detection.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Pilette, Ouadrhiri, Van Snick, Renauld, Staquet, Vaerman, Sibille: "Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).

    De Smedt, Verhasselt, Kerre, Vanhecke, Naessens, Leclercq, Renauld, Van Snick, Plum: "Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1761-7, (2000) (PubMed).

  • 抗原
    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
    别名
    CD129 / IL-9R alpha (IL9R 产品)
    别名
    CD129 antibody, IL-9R antibody, interleukin 9 receptor antibody, IL9R antibody, Il9r antibody
    背景
    Interleukin 9 receptor,CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.,IL9R
    基因ID
    3581
    UniProt
    Q01113
    途径
    JAK/STAT Signaling, Growth Factor Binding
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