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LY9 抗体

CD229 适用: 人 WB, FACS, IP, ICC, Func 宿主: 小鼠 Monoclonal HLy9-25 unconjugated
产品编号 ABIN2749218
发货至: 中国
  • 抗原 See all LY9 (CD229) 抗体
    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
    适用
    • 41
    • 5
    • 3
    宿主
    • 27
    • 15
    • 1
    小鼠
    克隆类型
    • 28
    • 15
    单克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LY9 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 13
    • 13
    • 11
    • 11
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
    特异性
    The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    内毒素水平
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    免疫原
    CD299-transfected 300.19 pre-B cell line
    克隆位点
    HLy9-25
    亚型
    IgG1
    Top Product
    Discover our top product CD229 Primary Antibody
  • 应用备注
    Functional application: Regulation of activation,
    Flow cytometry: Recommended dilution: 6-10 μg/mL, positive control: peripheral blood lymphocytes.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • de la Fuente, Tovar, Villamor, Zapater, Pizcueta, Campo, Bosch, Engel: "Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9." in: Blood, Vol. 97, Issue 11, pp. 3513-20, (2001) (PubMed).

  • 抗原
    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
    别名
    CD229 (CD229 产品)
    别名
    LY9 antibody, CD229 antibody, SLAMF3 antibody, hly9 antibody, mLY9 antibody, AI893573 antibody, Lgp100 antibody, Ly-9 antibody, T100 antibody, lymphocyte antigen 9 antibody, LY9 antibody, Ly9 antibody
    背景
    Lymphocyte antigen 9,CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.,SLAMF3, LY9
    基因ID
    4063
    UniProt
    Q9HBG7
    途径
    BCR Signaling
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