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Ki-67 抗体

MKI67 适用: 人, Cow IHC, WB, FACS, ICC 宿主: 小鼠 Monoclonal Ki-67 unconjugated
产品编号 ABIN2749188
发货至: 中国
  • 抗原 See all Ki-67 (MKI67) 抗体
    Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
    适用
    • 180
    • 67
    • 41
    • 4
    • 2
    • 2
    • 1
    • 1
    人, Cow
    宿主
    • 145
    • 38
    • 4
    • 3
    小鼠
    克隆类型
    • 136
    • 52
    单克隆
    标记
    • 83
    • 13
    • 13
    • 7
    • 7
    • 5
    • 5
    • 5
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    • 5
    • 5
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    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
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    • 2
    This Ki-67 antibody is un-conjugated
    应用范围
    • 83
    • 73
    • 65
    • 55
    • 53
    • 47
    • 36
    • 27
    • 26
    • 14
    • 12
    • 5
    • 5
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    • 2
    • 2
    • 1
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    Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    特异性
    The mouse monoclonal antibody Ki-67 recognizes Ki-67 antigen, a non-histone nuclear protein expressed exclusively in proliferating cells.
    交叉反应 (详细)
    Human, Bovine
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Nuclei of the Hodgkin lymphoma cell line L428
    克隆位点
    Ki-67
    亚型
    IgG1
    Top Product
    Discover our top product MKI67 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
    Immunocytochemistry: Paraformaldehyde fixation, recommended antibody concentration 1 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Schlüter, Duchrow, Wohlenberg, Becker, Key, Flad, Gerdes: "The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins." in: The Journal of cell biology, Vol. 123, Issue 3, pp. 513-22, (1993) (PubMed).

    Gerdes, Lemke, Baisch, Wacker, Schwab, Stein: "Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 133, Issue 4, pp. 1710-5, (1984) (PubMed).

    Gerdes, Schwab, Lemke, Stein: "Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation." in: International journal of cancer. Journal international du cancer, Vol. 31, Issue 1, pp. 13-20, (1983) (PubMed).

  • 抗原
    Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
    别名
    Ki-67 (MKI67 产品)
    别名
    MKI67 antibody, kia antibody, mki67 antibody, MGC132156 antibody, D630048A14Rik antibody, Ki-67 antibody, Ki67 antibody, KIA antibody, MIB-1 antibody, marker of proliferation Ki-67 antibody, marker of proliferation Ki-67 L homeolog antibody, marker of proliferation Ki-67 S homeolog antibody, antigen identified by monoclonal antibody Ki 67 antibody, antigen identified by monoclonal antibody Ki-67 antibody, nucleolar protein interacting with the FHA domain of MKI67 antibody, MKI67 antibody, mki67 antibody, mki67.L antibody, mki67.S antibody, Mki67 antibody, NIFK antibody
    背景
    Marker of proliferation Ki-67,Ki-67 is a highly protease-sensitive nuclear protein expressed in two isoforms (345 kDa and 395 kDa), both of which are identified by the antibody clone Ki-67. The Ki-67 antigen is essential for cell proliferation and its expression is restricted to the cycling cells. It is detected in G1, S, G2 and M phase, whereas it is absent in cells which are in G0 phase and it is not associated with DNA repair processes. Ki-67 thus represents an important tool for detection of proliferating cells, which is of great importance in tumor diagnostics and is commonly used as a prognostic factor in cancer studies.,KIA, MIB, Marker of proliferation Ki67, MKI67
    基因ID
    4288
    UniProt
    P46013
    途径
    Glycosaminoglycan Metabolic Process
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