The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.
交叉反应 (详细)
Human
纯化方法
Purified by protein-A affinity chromatography.
纯度
> 95 % (by SDS-PAGE)
免疫原
Recombinant fragment of human OPAL1 (amino acids 152-342)
D19Wsu162e antibody, Opal1 antibody, C10orf26 antibody, OPA1L antibody, OPAL1 antibody, RGD1305793 antibody, WW domain binding protein 1 like antibody, WW domain binding protein 1-like antibody, Wbp1l antibody, WBP1L antibody
背景
WW domain binding protein 1 like,OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.,WBP1L