CD160 抗体
(2 references)-
- 抗原 See all CD160 抗体
- CD160
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD160 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- The mouse monoclonal antibody BY55 recognizes an extracellular epitope of CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. The antibody detects both GPI-anchored and transmembrane form of CD160.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Human NK cell line YT2C2
- 克隆位点
- BY55
- 亚型
- IgM kappa
- Top Product
- Discover our top product CD160 Primary Antibody
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anti-CD160 (CD160) antibody (PE)
CD160 适用: 人 FACS 宿主: 小鼠 Monoclonal BY55 PE
anti-CD160 (CD160) (AA 81-159) antibodyCD160 适用: 人, 大鼠 WB, FACS, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) antibody (APC)CD160 适用: 人 FACS 宿主: 小鼠 Monoclonal BY55 APC
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD160 (CD160) (Internal Region) antibodyCD160 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 33-171) antibodyCD160 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-CD160 (CD160) (AA 27-136) antibodyCD160 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
: "BY55/CD160 cannot be considered a cytotoxic marker in cytomegalovirus-specific human CD8(+) T cells." in: Clinical and experimental immunology, Vol. 149, Issue 1, pp. 87-96, (2007) (PubMed).
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: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
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- 抗原
- CD160
- 别名
- CD160 (CD160 产品)
- 背景
- CD160 Molecule,CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.,NK1, NK28
- 基因ID
- 11126
- UniProt
- O95971
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